| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 9 | 6 | 4.26 | .307 | 1.31 | 8.1 | 3.7 | 8.8 | 133.0 | 120 | 64 | 63 | 15 | 54 | 130 | 1 | 0 | 0 | 1 | 10 | 3 | 3 | 3.80 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 19 | 19 | 8 | 7 | 3.50 | .267 | 1.08 | 7.7 | 2.1 | 7.9 | 136.1 | 116 | 56 | 53 | 15 | 31 | 120 | 5 | 0 | 0 | 1 | 10 | 2 | 2 | 3.40 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 83 | 19 | 19 | 10 | 6 | 3.27 | .281 | 1.16 | 8.1 | 2.4 | 4.6 | 148.2 | 134 | 60 | 54 | 13 | 39 | 75 | 3 | 0 | 0 | 0 | 13 | 1 | 2 | 3.94 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 19 | 19 | 12 | 4 | 3.14 | .270 | 1.10 | 6.2 | 3.7 | 7.8 | 137.2 | 95 | 51 | 48 | 14 | 56 | 119 | 3 | 0 | 0 | 1 | 14 | 2 | 3 | 3.86 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 46 | 17 | 17 | 10 | 4 | 4.31 | .313 | 1.36 | 8.6 | 3.7 | 6.9 | 112.2 | 107 | 58 | 54 | 10 | 46 | 86 | 2 | 0 | 0 | 1 | 9 | 1 | 2 | 3.88 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 48 | 0 | 1 | 1 | 2.15 | .256 | 1.01 | 6.0 | 3.2 | 9.2 | 54.1 | 36 | 13 | 13 | 3 | 19 | 55 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 2.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 24 | 0 | 3 | 1 | 1.29 | .232 | 0.90 | 4.3 | 3.9 | 8.1 | 21.0 | 10 | 3 | 3 | 0 | 9 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.48 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 14 | 0 | 1 | 2 | 1.08 | .254 | 1.02 | 6.8 | 2.8 | 4.5 | 16.2 | 12 | 2 | 2 | 0 | 5 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.94 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 9 | 0 | 0 | 0 | 4.32 | .265 | 1.08 | 4.5 | 5.6 | 10.1 | 8.1 | 4 | 4 | 4 | 3 | 5 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.50 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 10 | 0 | 1 | 0 | 3.38 | .294 | 1.25 | 7.9 | 3.4 | 3.9 | 16.0 | 14 | 6 | 6 | 3 | 6 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.69 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 34 | 0 | 4 | 3 | 3.03 | .277 | 1.15 | 8.0 | 2.6 | 9.8 | 35.2 | 31 | 12 | 12 | 1 | 10 | 38 | 0 | 18 | 2 | 0 | 0 | 0 | 3 | 2.06 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 6 | 0 | 1 | 0 | 2.35 | .188 | 0.70 | 4.3 | 2.0 | 4.3 | 23.0 | 11 | 6 | 6 | 2 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |