| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 11 | 11 | 6 | 2 | 3.50 | .285 | 1.18 | 7.7 | 3.0 | 9.3 | 69.1 | 59 | 28 | 27 | 9 | 23 | 71 | 1 | 0 | 0 | 1 | 7 | 1 | 0 | 3.68 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 11 | 11 | 2 | 6 | 4.09 | .299 | 1.27 | 8.2 | 3.3 | 4.2 | 83.2 | 76 | 41 | 38 | 11 | 30 | 39 | 3 | 0 | 0 | 1 | 6 | 1 | 2 | 4.90 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 11 | 11 | 3 | 6 | 5.58 | .342 | 1.56 | 10.5 | 3.5 | 6.0 | 79.0 | 92 | 51 | 49 | 14 | 31 | 53 | 1 | 0 | 0 | 0 | 4 | 0 | 2 | 5.14 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 11 | 10 | 2 | 5 | 4.80 | .364 | 1.70 | 9.5 | 5.9 | 7.5 | 60.0 | 63 | 33 | 32 | 8 | 39 | 50 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 5.07 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 60 | 11 | 11 | 4 | 3 | 5.51 | .348 | 1.48 | 9.6 | 3.9 | 5.1 | 63.2 | 67 | 41 | 39 | 7 | 27 | 36 | 0 | 0 | 0 | 0 | 5 | 8 | 5 | 4.97 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 25 | 0 | 1 | 2 | 6.35 | .384 | 1.84 | 13.2 | 3.5 | 10.3 | 28.1 | 41 | 20 | 20 | 7 | 11 | 32 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.25 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 24 | 0 | 0 | 0 | 3.33 | .330 | 1.48 | 9.4 | 4.1 | 8.6 | 24.1 | 25 | 9 | 9 | 2 | 11 | 23 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.54 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 22 | 0 | 2 | 2 | 4.74 | .362 | 1.70 | 10.9 | 4.9 | 7.5 | 24.2 | 29 | 13 | 13 | 5 | 13 | 20 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.67 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 9 | 0 | 0 | 3 | 6.52 | .396 | 1.86 | 14.0 | 4.0 | 5.0 | 9.2 | 14 | 7 | 7 | 2 | 4 | 5 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 6.44 |