| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 20 | 20 | 11 | 6 | 4.16 | .282 | 1.14 | 7.2 | 3.1 | 7.7 | 134.0 | 107 | 62 | 62 | 21 | 46 | 115 | 7 | 0 | 0 | 1 | 11 | 5 | 0 | 4.46 |
| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 19 | 19 | 11 | 4 | 2.80 | .261 | 1.06 | 6.9 | 2.7 | 7.1 | 141.2 | 108 | 49 | 44 | 9 | 42 | 112 | 3 | 0 | 0 | 0 | 16 | 0 | 2 | 3.13 |
| SP | Brown, M.Brown, Mordecai † >> | 32 | 1908 | R | 85 | 19 | 19 | 14 | 4 | 3.01 | .266 | 1.06 | 7.4 | 2.3 | 4.0 | 143.2 | 117 | 49 | 48 | 5 | 36 | 63 | 6 | 0 | 0 | 1 | 16 | 3 | 3 | 3.39 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 17 | 17 | 10 | 5 | 5.23 | .311 | 1.34 | 10.1 | 2.1 | 4.7 | 118.2 | 132 | 73 | 69 | 16 | 27 | 61 | 4 | 0 | 0 | 0 | 6 | 2 | 1 | 4.47 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 35 | 0 | 1 | 1 | 2.36 | .248 | 0.96 | 6.6 | 2.1 | 9.8 | 34.1 | 25 | 9 | 9 | 1 | 8 | 37 | 0 | 26 | 2 | 0 | 0 | 1 | 1 | 2.00 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 5 | 0 | 2 | 0 | 1.50 | .143 | 0.50 | 1.5 | 3.0 | 10.5 | 6.0 | 1 | 1 | 1 | 1 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 12 | 0 | 0 | 1 | 3.18 | .292 | 1.24 | 9.0 | 2.5 | 4.9 | 11.1 | 11 | 4 | 4 | 1 | 3 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 29 | 0 | 1 | 2 | 4.15 | .305 | 1.32 | 8.4 | 3.6 | 8.1 | 30.1 | 28 | 15 | 14 | 4 | 12 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.13 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 40 | 10 | 0 | 0 | 0 | 4.35 | .317 | 1.35 | 8.3 | 4.1 | 7.9 | 51.2 | 47 | 32 | 25 | 6 | 23 | 45 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4.24 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 4 | 3 | 1 | 1 | 8.53 | .333 | 1.50 | 12.8 | 1.5 | 3.0 | 12.2 | 17 | 12 | 12 | 4 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.17 |