| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 17 | 17 | 2 | 6 | 4.02 | .306 | 1.28 | 8.1 | 3.4 | 7.5 | 103.0 | 93 | 48 | 46 | 12 | 39 | 86 | 0 | 0 | 0 | 0 | 12 | 4 | 0 | 4.10 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 17 | 17 | 7 | 8 | 3.41 | .246 | 0.95 | 6.7 | 1.9 | 8.1 | 113.1 | 84 | 45 | 43 | 19 | 24 | 102 | 4 | 0 | 0 | 1 | 9 | 3 | 2 | 4.10 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 16 | 16 | 4 | 4 | 5.50 | .347 | 1.53 | 11.3 | 2.6 | 4.6 | 88.1 | 110 | 60 | 54 | 10 | 25 | 45 | 0 | 0 | 0 | 0 | 6 | 6 | 1 | 4.51 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 16 | 16 | 2 | 4 | 5.28 | .329 | 1.40 | 9.8 | 2.8 | 5.2 | 87.0 | 95 | 51 | 51 | 9 | 27 | 50 | 1 | 0 | 0 | 1 | 6 | 6 | 1 | 4.33 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 41 | 0 | 3 | 4 | 2.08 | .278 | 1.13 | 6.6 | 3.6 | 8.8 | 52.0 | 38 | 13 | 12 | 4 | 21 | 51 | 0 | 20 | 2 | 0 | 0 | 1 | 0 | 3.31 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 40 | 0 | 2 | 4 | 5.23 | .307 | 1.28 | 8.8 | 2.9 | 7.9 | 41.1 | 40 | 25 | 24 | 9 | 13 | 36 | 0 | 3 | 5 | 0 | 0 | 2 | 0 | 5.20 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 48 | 0 | 6 | 1 | 2.67 | .284 | 1.14 | 6.2 | 4.1 | 4.5 | 64.0 | 44 | 20 | 19 | 7 | 29 | 32 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 4.92 |