| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 20 | 20 | 11 | 7 | 4.24 | .272 | 1.09 | 7.5 | 2.4 | 7.0 | 144.1 | 120 | 68 | 68 | 21 | 38 | 112 | 2 | 0 | 0 | 0 | 12 | 4 | 2 | 4.22 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 19 | 19 | 9 | 10 | 3.88 | .279 | 1.13 | 7.7 | 2.4 | 5.4 | 148.1 | 127 | 64 | 64 | 12 | 40 | 89 | 8 | 0 | 0 | 2 | 10 | 5 | 0 | 3.76 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 18 | 18 | 7 | 5 | 4.48 | .316 | 1.37 | 9.0 | 3.4 | 7.9 | 128.2 | 128 | 64 | 64 | 13 | 48 | 113 | 2 | 0 | 0 | 1 | 9 | 2 | 4 | 3.73 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 49 | 0 | 1 | 3 | 3.32 | .286 | 1.17 | 7.7 | 2.9 | 8.9 | 62.1 | 53 | 23 | 23 | 8 | 20 | 61 | 0 | 10 | 4 | 0 | 0 | 2 | 0 | 3.77 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 36 | 0 | 2 | 2 | 2.39 | .254 | 0.96 | 6.6 | 2.0 | 9.4 | 49.0 | 36 | 13 | 13 | 3 | 11 | 51 | 0 | 3 | 0 | 0 | 0 | 3 | 3 | 2.57 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 23 | 0 | 2 | 2 | 4.62 | .372 | 1.74 | 10.8 | 5.0 | 7.2 | 25.1 | 30 | 14 | 13 | 2 | 14 | 20 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.24 |
| RP | Valverde, J.Valverde, Jose # >> | 24 | 2003 | R | 64 | 30 | 0 | 1 | 4 | 5.29 | .340 | 1.55 | 8.7 | 5.3 | 10.7 | 32.1 | 31 | 21 | 19 | 4 | 19 | 38 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 4.03 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 10 | 0 | 1 | 2 | 4.76 | .292 | 1.24 | 6.4 | 4.8 | 4.8 | 17.0 | 12 | 9 | 9 | 2 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.06 |