| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 26 | 26 | 9 | 10 | 3.86 | .259 | 1.04 | 7.7 | 1.6 | 7.6 | 193.2 | 166 | 88 | 83 | 24 | 35 | 162 | 6 | 0 | 0 | 1 | 16 | 2 | 6 | 3.51 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 25 | 25 | 11 | 8 | 3.90 | .286 | 1.17 | 7.8 | 2.8 | 4.6 | 173.0 | 150 | 87 | 75 | 15 | 53 | 89 | 5 | 0 | 0 | 1 | 15 | 5 | 7 | 4.10 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 25 | 24 | 11 | 9 | 4.15 | .306 | 1.29 | 8.0 | 3.7 | 4.9 | 167.0 | 148 | 84 | 77 | 24 | 68 | 90 | 1 | 1 | 0 | 0 | 13 | 5 | 2 | 5.10 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 24 | 22 | 7 | 12 | 5.19 | .334 | 1.50 | 8.7 | 4.8 | 7.4 | 144.0 | 139 | 89 | 83 | 18 | 77 | 118 | 0 | 0 | 0 | 0 | 11 | 1 | 10 | 4.61 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 63 | 0 | 3 | 1 | 1.88 | .234 | 0.90 | 5.4 | 2.8 | 9.5 | 72.0 | 43 | 16 | 15 | 6 | 22 | 76 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 2.93 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 41 | 0 | 1 | 2 | 1.57 | .280 | 1.14 | 5.6 | 4.8 | 8.2 | 34.1 | 21 | 6 | 6 | 2 | 18 | 31 | 0 | 8 | 0 | 0 | 0 | 1 | 3 | 3.62 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 24 | 0 | 2 | 2 | 3.72 | .293 | 1.21 | 6.5 | 4.3 | 8.1 | 29.0 | 21 | 12 | 12 | 4 | 14 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.55 |
| RP | Charlton, N.Charlton, Norm >> | 30 | 1993 | L | 31 | 72 | 0 | 3 | 0 | 2.28 | .290 | 1.19 | 7.6 | 3.2 | 9.5 | 51.1 | 43 | 16 | 13 | 5 | 18 | 54 | 0 | 1 | 1 | 0 | 0 | 2 | 8 | 3.33 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 18 | 1 | 3 | 1 | 3.83 | .313 | 1.33 | 7.7 | 4.3 | 7.1 | 56.1 | 48 | 26 | 24 | 1 | 27 | 44 | 0 | 3 | 0 | 0 | 0 | 2 | 2 | 3.21 |