| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 38 | 38 | 17 | 11 | 3.21 | .251 | 1.00 | 6.5 | 2.5 | 8.1 | 258.0 | 185 | 95 | 92 | 30 | 72 | 233 | 6 | 0 | 0 | 2 | 28 | 3 | 4 | 3.58 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 25 | 25 | 10 | 10 | 4.74 | .322 | 1.40 | 9.4 | 3.2 | 4.5 | 161.1 | 169 | 90 | 85 | 18 | 57 | 80 | 1 | 0 | 0 | 0 | 14 | 4 | 4 | 4.60 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 34 | 34 | 18 | 7 | 4.06 | .295 | 1.21 | 7.7 | 3.2 | 5.4 | 253.0 | 216 | 122 | 114 | 28 | 90 | 151 | 8 | 0 | 0 | 2 | 16 | 12 | 3 | 4.45 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 71 | 0 | 5 | 10 | 2.71 | .265 | 1.07 | 6.7 | 3.0 | 8.4 | 73.0 | 54 | 23 | 22 | 2 | 24 | 68 | 0 | 44 | 4 | 0 | 0 | 1 | 2 | 2.52 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 65 | 0 | 4 | 4 | 3.41 | .270 | 1.11 | 6.5 | 3.5 | 9.0 | 71.1 | 51 | 29 | 27 | 6 | 28 | 71 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 48 | 0 | 1 | 3 | 4.32 | .355 | 1.65 | 10.6 | 4.4 | 6.3 | 33.1 | 39 | 18 | 16 | 8 | 16 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6.21 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 27 | 0 | 3 | 0 | 1.48 | .189 | 0.70 | 3.4 | 3.0 | 8.3 | 24.1 | 9 | 4 | 4 | 3 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.79 |