| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 12 | 13 | 3.61 | .287 | 1.19 | 8.0 | 2.7 | 8.8 | 214.2 | 191 | 91 | 86 | 26 | 65 | 210 | 1 | 0 | 0 | 1 | 19 | 3 | 0 | 3.57 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 32 | 32 | 16 | 13 | 4.15 | .284 | 1.17 | 7.6 | 3.0 | 5.1 | 236.2 | 198 | 115 | 109 | 23 | 78 | 133 | 15 | 0 | 0 | 3 | 16 | 5 | 2 | 4.19 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 14 | 8 | 4.22 | .299 | 1.24 | 8.8 | 2.4 | 7.5 | 222.0 | 218 | 108 | 104 | 34 | 58 | 184 | 6 | 0 | 0 | 1 | 16 | 8 | 4 | 4.23 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 31 | 30 | 17 | 10 | 3.94 | .297 | 1.23 | 8.5 | 2.5 | 5.1 | 233.0 | 220 | 105 | 102 | 30 | 66 | 131 | 10 | 0 | 0 | 0 | 12 | 10 | 3 | 4.53 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 74 | 0 | 5 | 4 | 4.91 | .309 | 1.33 | 8.8 | 3.2 | 8.1 | 88.0 | 86 | 48 | 48 | 10 | 31 | 79 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.77 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 91 | 60 | 0 | 3 | 3 | 2.99 | .270 | 1.08 | 7.3 | 2.5 | 9.3 | 69.1 | 56 | 23 | 23 | 13 | 19 | 71 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 4.30 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 25 | 0 | 2 | 1 | 1.74 | .225 | 0.87 | 5.5 | 2.3 | 8.4 | 31.0 | 19 | 6 | 6 | 0 | 8 | 29 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 1.90 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 17 | 0 | 1 | 2 | 2.95 | .321 | 1.36 | 7.5 | 5.0 | 5.5 | 18.1 | 15 | 6 | 6 | 1 | 10 | 11 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.33 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 2 | 0 | 0 | 0 | 38.57 | .632 | 5.14 | 45.0 | 9.0 | 9.0 | 2.1 | 10 | 10 | 10 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 32 | 22 | 0 | 1 | 0 | 3.65 | .245 | 0.97 | 6.0 | 3.0 | 4.1 | 24.2 | 16 | 10 | 10 | 3 | 8 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.71 |