| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 25 | 25 | 9 | 14 | 4.75 | .309 | 1.33 | 8.7 | 3.2 | 8.1 | 178.0 | 172 | 97 | 94 | 28 | 64 | 160 | 8 | 0 | 0 | 1 | 11 | 3 | 4 | 4.38 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 24 | 24 | 7 | 7 | 4.20 | .290 | 1.20 | 8.7 | 2.1 | 4.7 | 143.2 | 138 | 69 | 67 | 21 | 34 | 75 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 4.66 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 84 | 24 | 24 | 9 | 9 | 5.35 | .345 | 1.56 | 10.2 | 3.9 | 6.3 | 112.2 | 127 | 76 | 67 | 12 | 49 | 78 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 4.37 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 62 | 0 | 4 | 1 | 4.27 | .271 | 1.10 | 8.0 | 2.0 | 8.4 | 78.0 | 69 | 38 | 37 | 9 | 17 | 73 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.32 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 57 | 0 | 6 | 3 | 2.70 | .298 | 1.26 | 8.2 | 3.1 | 9.8 | 70.0 | 64 | 26 | 21 | 8 | 24 | 76 | 0 | 4 | 7 | 0 | 0 | 1 | 2 | 3.39 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 41 | 0 | 1 | 3 | 2.57 | .263 | 1.04 | 5.3 | 4.0 | 9.5 | 56.0 | 33 | 16 | 16 | 3 | 25 | 59 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.04 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 37 | 0 | 2 | 2 | 2.65 | .243 | 0.94 | 6.5 | 1.9 | 8.8 | 51.0 | 37 | 15 | 15 | 3 | 11 | 50 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.51 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 25 | 0 | 0 | 1 | 4.71 | .306 | 1.33 | 8.4 | 3.9 | 7.4 | 28.2 | 26 | 17 | 15 | 0 | 12 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.64 |