| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 11 | 11 | 4 | 5 | 3.94 | .304 | 1.28 | 8.8 | 2.7 | 9.0 | 80.0 | 78 | 35 | 35 | 4 | 24 | 80 | 2 | 0 | 0 | 1 | 5 | 3 | 4 | 2.66 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 11 | 11 | 8 | 1 | 2.94 | .266 | 1.07 | 6.9 | 2.9 | 8.4 | 85.2 | 65 | 30 | 28 | 7 | 27 | 79 | 4 | 0 | 0 | 0 | 8 | 1 | 1 | 3.20 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 11 | 11 | 4 | 2 | 4.19 | .304 | 1.31 | 8.2 | 3.7 | 9.4 | 68.2 | 62 | 34 | 32 | 9 | 28 | 71 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 3.87 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 11 | 11 | 2 | 3 | 4.64 | .302 | 1.28 | 9.4 | 2.3 | 4.1 | 75.2 | 78 | 39 | 39 | 8 | 19 | 34 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.28 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 30 | 0 | 1 | 2 | 2.23 | .288 | 1.19 | 6.8 | 4.1 | 9.2 | 40.1 | 30 | 11 | 10 | 1 | 18 | 41 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 2.70 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 21 | 0 | 4 | 1 | 6.26 | .343 | 1.52 | 8.6 | 5.1 | 9.4 | 23.0 | 22 | 17 | 16 | 5 | 13 | 24 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 5.57 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 18 | 0 | 1 | 3 | 3.72 | .333 | 1.50 | 9.9 | 3.8 | 10.4 | 19.1 | 21 | 10 | 8 | 4 | 8 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.68 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 4 | 0 | 0 | 1 | 1.50 | .333 | 1.50 | 9.0 | 4.5 | 7.5 | 6.0 | 6 | 1 | 1 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.83 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 3 | 0 | 1 | 1 | 6.43 | .344 | 1.57 | 10.3 | 3.9 | 6.4 | 7.0 | 8 | 5 | 5 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.71 |