| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 6 | 6 | 3 | 2 | 3.40 | .246 | 0.96 | 6.0 | 2.6 | 9.2 | 45.0 | 30 | 17 | 17 | 6 | 13 | 46 | 1 | 0 | 0 | 0 | 4 | 1 | 4 | 3.62 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 8 | 8 | 5 | 2 | 1.57 | .217 | 0.83 | 5.0 | 2.5 | 7.7 | 68.2 | 38 | 13 | 12 | 2 | 19 | 58 | 6 | 0 | 0 | 3 | 7 | 0 | 2 | 2.51 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 7 | 7 | 3 | 4 | 5.40 | .326 | 1.39 | 8.1 | 4.5 | 4.9 | 48.1 | 43 | 30 | 29 | 7 | 24 | 26 | 1 | 0 | 0 | 1 | 2 | 3 | 1 | 5.50 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 7 | 7 | 3 | 4 | 3.86 | .300 | 1.29 | 8.2 | 3.5 | 5.7 | 46.2 | 42 | 23 | 20 | 6 | 18 | 29 | 2 | 0 | 0 | 1 | 4 | 0 | 0 | 4.61 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 6 | 6 | 0 | 5 | 8.27 | .358 | 1.65 | 12.4 | 2.4 | 4.6 | 37.0 | 51 | 36 | 34 | 7 | 10 | 19 | 2 | 0 | 0 | 0 | 0 | 1 | 2 | 5.32 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 18 | 0 | 1 | 1 | 3.48 | .225 | 0.87 | 5.4 | 2.7 | 7.7 | 20.2 | 12 | 8 | 8 | 2 | 6 | 17 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.50 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 6 | 0 | 0 | 0 | 1.93 | .263 | 1.07 | 7.0 | 3.0 | 9.0 | 9.1 | 7 | 2 | 2 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 4 | 0 | 1 | 0 | 3.86 | .364 | 1.71 | 13.5 | 4.5 | 11.3 | 4.2 | 6 | 4 | 2 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.25 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 6 | 0 | 0 | 0 | 5.00 | .341 | 1.56 | 13.0 | 1.0 | 6.0 | 9.0 | 13 | 10 | 5 | 3 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.33 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 5 | 0 | 0 | 0 | 4.05 | .333 | 1.35 | 9.0 | 4.5 | 10.5 | 6.2 | 6 | 3 | 3 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.67 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 3 | 2 | 1 | 1 | 6.61 | .329 | 1.41 | 11.3 | 1.7 | 5.1 | 16.1 | 20 | 14 | 12 | 4 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.88 |