| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 11 | 11 | 2 | 6 | 3.54 | .304 | 1.27 | 9.0 | 2.5 | 5.3 | 68.2 | 68 | 27 | 27 | 9 | 19 | 40 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.51 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 11 | 11 | 4 | 5 | 4.43 | .295 | 1.24 | 8.7 | 2.4 | 3.3 | 63.0 | 61 | 33 | 31 | 6 | 17 | 23 | 1 | 0 | 0 | 0 | 6 | 1 | 4 | 4.37 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 11 | 11 | 3 | 4 | 3.66 | .279 | 1.15 | 8.2 | 2.2 | 3.0 | 66.1 | 60 | 28 | 27 | 5 | 16 | 22 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 4.09 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 26 | 0 | 2 | 3 | 4.13 | .290 | 1.22 | 8.7 | 2.5 | 8.7 | 32.2 | 31 | 16 | 15 | 6 | 9 | 31 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 4.34 |
| SU | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 30 | 0 | 1 | 3 | 3.41 | .264 | 1.08 | 7.7 | 2.1 | 8.5 | 34.1 | 29 | 16 | 13 | 5 | 8 | 32 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 35 | 0 | 4 | 0 | 2.83 | .291 | 1.23 | 8.3 | 2.9 | 7.5 | 41.1 | 38 | 15 | 13 | 4 | 13 | 34 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.56 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 26 | 0 | 1 | 2 | 6.21 | .338 | 1.44 | 6.8 | 6.3 | 10.9 | 33.1 | 25 | 23 | 23 | 2 | 23 | 40 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 3.73 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 23 | 0 | 1 | 1 | 3.49 | .274 | 0.99 | 7.1 | 1.9 | 7.7 | 28.1 | 22 | 11 | 11 | 3 | 6 | 24 | 0 | 0 | 2 | 0 | 0 | 4 | 0 | 3.75 |