| SP | Cicotte, E.Cicotte, Eddie >> | 35 | 1919 | R | 79 | 20 | 20 | 9 | 9 | 3.75 | .284 | 1.14 | 8.3 | 2.0 | 5.4 | 139.1 | 128 | 61 | 58 | 12 | 31 | 84 | 3 | 0 | 0 | 1 | 11 | 7 | 0 | 3.73 |
| SP | Williams, L.Williams, Lefty >> | 26 | 1919 | L | 67 | 18 | 18 | 6 | 9 | 4.26 | .322 | 1.42 | 10.3 | 2.4 | 4.5 | 129.0 | 148 | 64 | 61 | 16 | 35 | 64 | 2 | 0 | 0 | 1 | 9 | 1 | 0 | 4.46 |
| SP | Buehrle, M.Buehrle, Mark >> | 26 | 2005 | L | 38 | 6 | 4 | 1 | 3 | 4.94 | .326 | 1.35 | 10.5 | 1.7 | 5.2 | 31.0 | 36 | 17 | 17 | 5 | 6 | 18 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 4.81 |
| SP | Kerr, D.Kerr, Dickey # >> | 26 | 1919 | L | 25 | 19 | 19 | 4 | 9 | 4.54 | .317 | 1.39 | 9.4 | 3.1 | 5.9 | 109.0 | 114 | 60 | 55 | 11 | 37 | 72 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.04 |
| SP | Lowdermilk, G.Lowdermilk, Grover >> | 34 | 1919 | R | 22 | 18 | 18 | 1 | 6 | 4.97 | .360 | 1.67 | 9.8 | 5.2 | 5.0 | 76.0 | 83 | 43 | 42 | 9 | 44 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.21 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 88 | 58 | 0 | 3 | 1 | 3.83 | .365 | 1.72 | 9.9 | 5.8 | 5.8 | 51.2 | 56 | 22 | 22 | 2 | 33 | 33 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.16 |
| RP | Hermanson, D.Hermanson, Dustin >> | 33 | 2005 | R | 59 | 41 | 0 | 0 | 2 | 5.62 | .321 | 1.34 | 8.3 | 4.0 | 2.9 | 41.2 | 38 | 26 | 26 | 8 | 18 | 13 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 6.44 |
| CL | Hernandez, R.Hernandez, Roberto † >> | 29 | 1993 | R | 63 | 37 | 0 | 2 | 5 | 2.13 | .245 | 0.95 | 5.7 | 2.8 | 7.3 | 38.0 | 24 | 15 | 9 | 3 | 12 | 31 | 0 | 23 | 3 | 0 | 0 | 1 | 0 | 3.42 |
| RP | Radinsky, S.Radinsky, Scott >> | 25 | 1993 | L | 11 | 62 | 0 | 1 | 1 | 6.14 | .358 | 1.67 | 10.9 | 4.3 | 7.1 | 29.1 | 35 | 21 | 20 | 5 | 14 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.10 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 31 | 2005 | R | 10 | 14 | 0 | 0 | 1 | 11.85 | .423 | 2.20 | 18.0 | 2.8 | 9.7 | 13.2 | 26 | 18 | 18 | 4 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.77 |
| SP | McCaskill, K.McCaskill, Kirk >> | 32 | 1993 | R | 4 | 22 | 1 | 6 | 2 | 6.91 | .357 | 1.65 | 11.2 | 3.8 | 6.7 | 54.2 | 67 | 45 | 42 | 11 | 23 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.50 |