| SP | Verlander, J.Verlander, Justin >> | 35 | 2018 | R | 100 | 25 | 25 | 8 | 11 | 3.15 | .286 | 1.17 | 8.1 | 2.5 | 8.0 | 157.1 | 141 | 56 | 55 | 9 | 43 | 140 | 0 | 0 | 0 | 0 | 18 | 5 | 2 | 2.88 |
| SP | Seaver, T.Seaver, Tom # >> | 36 | 1980 | R | 80 | 24 | 24 | 6 | 6 | 5.19 | .334 | 1.50 | 9.9 | 3.6 | 4.7 | 119.2 | 131 | 72 | 69 | 10 | 48 | 62 | 0 | 0 | 0 | 0 | 8 | 1 | 3 | 4.29 |
| SP | Cheney, L.Cheney, Larry >> | 27 | 1913 | R | 62 | 24 | 24 | 5 | 9 | 5.67 | .344 | 1.53 | 10.5 | 3.3 | 6.0 | 108.0 | 126 | 71 | 68 | 8 | 39 | 72 | 0 | 0 | 0 | 0 | 3 | 5 | 3 | 3.85 |
| RP | Herrera, K.Herrera, Kelvin >> | 26 | 2016 | R | 89 | 61 | 0 | 6 | 1 | 4.04 | .324 | 1.42 | 10.0 | 2.7 | 7.6 | 69.0 | 77 | 33 | 31 | 7 | 21 | 58 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.59 |
| RP | Lorenzen, M.Lorenzen, Michael >> | 24 | 2016 | R | 78 | 57 | 0 | 8 | 1 | 4.15 | .309 | 1.31 | 8.9 | 2.9 | 6.8 | 65.0 | 64 | 30 | 30 | 4 | 21 | 49 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 3.35 |
| RP | Abernathy, T.Abernathy, Ted >> | 35 | 1968 | R | 53 | 27 | 0 | 3 | 0 | 1.56 | .212 | 0.81 | 5.3 | 2.1 | 2.6 | 34.2 | 20 | 9 | 6 | 1 | 8 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.50 |
| RP | Broxton, J.Broxton, Jonathan >> | 28 | 2012 | R | 40 | 16 | 0 | 1 | 2 | 2.53 | .312 | 1.31 | 8.1 | 3.9 | 6.4 | 21.1 | 19 | 6 | 6 | 2 | 9 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.24 |
| CL | Balfour, G.Balfour, Grant † >> | 35 | 2012 | R | 99 | 53 | 0 | 4 | 5 | 1.98 | .263 | 1.05 | 5.8 | 3.7 | 6.4 | 59.0 | 38 | 16 | 13 | 0 | 24 | 42 | 0 | 30 | 8 | 0 | 0 | 1 | 1 | 2.85 |
| SU | Urbina, U.Urbina, Ugueth >> | 29 | 2003 | R | 85 | 41 | 0 | 0 | 2 | 3.32 | .278 | 1.16 | 7.2 | 3.4 | 8.8 | 40.2 | 32 | 15 | 15 | 2 | 15 | 39 | 0 | 3 | 5 | 0 | 0 | 0 | 4 | 2.83 |