| SP | Smoltz, J.Smoltz, John >> | 25 | 1992 | R | 90 | 34 | 34 | 12 | 11 | 4.31 | .325 | 1.44 | 9.2 | 3.8 | 6.1 | 215.0 | 220 | 107 | 103 | 25 | 90 | 145 | 8 | 0 | 0 | 0 | 20 | 0 | 8 | 4.42 |
| SP | Flanagan, M.Flanagan, Mike >> | 28 | 1979 | L | 80 | 33 | 33 | 9 | 15 | 4.84 | .335 | 1.49 | 10.3 | 3.1 | 6.3 | 187.2 | 214 | 109 | 101 | 26 | 65 | 130 | 1 | 0 | 0 | 0 | 19 | 4 | 1 | 4.52 |
| SP | Boland, B.Boland, Bernie >> | 27 | 1919 | R | 68 | 32 | 32 | 6 | 14 | 4.30 | .324 | 1.40 | 9.5 | 3.1 | 4.5 | 188.1 | 199 | 103 | 90 | 20 | 65 | 94 | 1 | 0 | 0 | 0 | 20 | 7 | 3 | 4.53 |
| SP | Zachary, T.Zachary, Tom >> | 28 | 1924 | L | 63 | 32 | 32 | 5 | 12 | 7.00 | .366 | 1.71 | 11.7 | 3.8 | 4.9 | 146.2 | 189 | 117 | 114 | 23 | 62 | 79 | 0 | 0 | 0 | 0 | 10 | 3 | 6 | 5.30 |
| SP | Buehrle, M.Buehrle, Mark >> | 36 | 2015 | L | 52 | 32 | 31 | 9 | 15 | 4.90 | .309 | 1.34 | 9.9 | 2.2 | 4.9 | 161.2 | 177 | 93 | 88 | 28 | 39 | 87 | 1 | 0 | 0 | 0 | 15 | 1 | 0 | 4.93 |
| CL | Hendriks, L.Hendriks, Liam # >> | 33 | 2022 | R | 94 | 89 | 0 | 2 | 8 | 4.83 | .299 | 1.28 | 9.0 | 2.5 | 9.9 | 110.0 | 110 | 63 | 59 | 14 | 31 | 121 | 0 | 14 | 6 | 0 | 0 | 0 | 10 | 3.30 |
| RP | Soria, J.Soria, Joakim >> | 34 | 2018 | R | 79 | 107 | 0 | 5 | 2 | 5.12 | .331 | 1.46 | 10.8 | 2.4 | 8.8 | 114.1 | 137 | 66 | 65 | 14 | 30 | 111 | 0 | 4 | 2 | 0 | 0 | 3 | 3 | 3.52 |
| SU | Wuertz, M.Wuertz, Michael >> | 27 | 2005 | R | 62 | 96 | 0 | 7 | 9 | 7.98 | .413 | 2.07 | 11.7 | 7.1 | 7.9 | 93.2 | 121 | 86 | 83 | 14 | 73 | 82 | 0 | 8 | 11 | 0 | 0 | 4 | 5 | 5.68 |
| RP | Holland, A.Holland, Al >> | 32 | 1984 | L | 71 | 102 | 0 | 3 | 2 | 4.14 | .311 | 1.33 | 9.1 | 2.9 | 6.2 | 117.1 | 118 | 57 | 54 | 13 | 38 | 81 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 4.11 |