| SP | Gausman, K.Gausman, Kevin >> | 30 | 2021 | R | 91 | 33 | 33 | 14 | 10 | 3.56 | .304 | 1.28 | 8.6 | 2.9 | 9.1 | 205.0 | 197 | 84 | 81 | 32 | 65 | 207 | 0 | 0 | 0 | 0 | 20 | 6 | 3 | 4.05 |
| SP | Garrelts, S.Garrelts, Scott † >> | 28 | 1989 | R | 88 | 34 | 34 | 18 | 7 | 3.88 | .303 | 1.27 | 8.5 | 3.0 | 6.3 | 225.0 | 212 | 98 | 97 | 22 | 74 | 158 | 1 | 0 | 0 | 0 | 21 | 7 | 8 | 3.95 |
| SP | DeSclafani, A.DeSclafani, Anthony † # >> | 31 | 2021 | R | 75 | 31 | 31 | 17 | 7 | 3.61 | .281 | 1.16 | 7.4 | 3.0 | 6.9 | 172.0 | 142 | 71 | 69 | 26 | 57 | 132 | 1 | 0 | 0 | 0 | 16 | 3 | 3 | 4.48 |
| RP | Garcia, J.Garcia, Jarlin >> | 28 | 2021 | L | 91 | 88 | 0 | 7 | 4 | 3.60 | .285 | 1.17 | 8.0 | 2.6 | 7.4 | 127.2 | 113 | 54 | 51 | 15 | 37 | 105 | 0 | 2 | 2 | 0 | 0 | 3 | 6 | 3.83 |
| RP | Watson, T.Watson, Tony >> | 36 | 2021 | L | 81 | 74 | 0 | 4 | 1 | 3.21 | .300 | 1.26 | 7.2 | 4.2 | 6.7 | 73.0 | 58 | 26 | 26 | 8 | 34 | 54 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.42 |
| RP | Leone, D.Leone, Dominic >> | 29 | 2021 | R | 76 | 53 | 0 | 4 | 2 | 4.63 | .313 | 1.33 | 7.7 | 4.3 | 8.0 | 56.1 | 48 | 30 | 29 | 8 | 27 | 50 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 4.63 |
| CL | Bedrosian, S.Bedrosian, Steve † >> | 32 | 1989 | R | 68 | 63 | 0 | 3 | 6 | 4.63 | .327 | 1.41 | 8.1 | 4.7 | 7.8 | 58.1 | 52 | 32 | 30 | 7 | 30 | 50 | 0 | 39 | 7 | 0 | 0 | 3 | 0 | 4.55 |
| RP | Wisler, M.Wisler, Matt >> | 28 | 2021 | R | 63 | 44 | 0 | 3 | 0 | 2.86 | .278 | 1.13 | 6.8 | 3.4 | 10.1 | 50.1 | 38 | 16 | 16 | 4 | 19 | 56 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.00 |
| RP | Littell, Z.Littell, Zack >> | 25 | 2021 | R | 61 | 42 | 0 | 3 | 1 | 3.17 | .322 | 1.41 | 7.5 | 5.3 | 7.3 | 48.1 | 40 | 17 | 17 | 6 | 28 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.81 |