| SP | Walsh, E.Walsh, Ed-CHA + >> | 26 | 1904 | R | 89 | 13 | 13 | 7 | 5 | 3.09 | .267 | 1.08 | 7.7 | 2.0 | 8.1 | 99.0 | 85 | 34 | 34 | 10 | 22 | 89 | 6 | 0 | 0 | 3 | 9 | 1 | 0 | 3.21 |
| SP | Kopech, M.Kopech, Michael >> | 29 | 2022 | R | 85 | 12 | 12 | 5 | 3 | 3.24 | .283 | 1.12 | 7.4 | 2.8 | 6.1 | 77.2 | 63 | 32 | 28 | 7 | 24 | 52 | 0 | 0 | 0 | 0 | 7 | 5 | 1 | 3.96 |
| SP | Cannon, J.Cannon, Jonathan + >> | 24 | 2024 | R | 69 | 11 | 11 | 2 | 3 | 4.70 | .310 | 1.32 | 10.0 | 1.8 | 6.8 | 69.0 | 77 | 38 | 36 | 14 | 14 | 52 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 4.83 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 55 | 8 | 8 | 4 | 3 | 4.44 | .317 | 1.39 | 10.0 | 2.7 | 11.7 | 46.2 | 51 | 25 | 23 | 10 | 14 | 60 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 4.13 |
| RP | Lopez, R.Lopez, Reynaldo >> | 31 | 2022 | R | 64 | 19 | 0 | 1 | 1 | 2.42 | .243 | 0.88 | 5.2 | 2.8 | 8.0 | 26.0 | 15 | 7 | 7 | 0 | 8 | 23 | 0 | 5 | 1 | 0 | 0 | 2 | 2 | 2.38 |
| RP | Santos, G.Santos, Gregory + >> | 25 | 2023 | R | 48 | 13 | 0 | 0 | 2 | 6.75 | .273 | 1.13 | 10.4 | 0.0 | 9.7 | 13.1 | 15 | 10 | 10 | 6 | 0 | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 6.85 |
| RP | Soroka, M.Soroka, Mike >> | 27 | 2024 | R | 50 | 12 | 0 | 0 | 1 | 7.08 | .351 | 1.52 | 11.3 | 2.7 | 9.9 | 20.1 | 25 | 17 | 16 | 5 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 5.25 |
| SP | Buehrle, M.Buehrle, Mark-CHA + >> | 23 | 2001 | L | 47 | 5 | 0 | 0 | 0 | 5.66 | .326 | 1.45 | 11.3 | 2.3 | 5.9 | 20.2 | 25 | 14 | 13 | 8 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.65 |
| SP | Giolito, L.Giolito, Lucas + >> | 30 | 2022 | R | 48 | 3 | 0 | 0 | 1 | 9.00 | .500 | 3.00 | 18.0 | 9.0 | 9.0 | 2.0 | 4 | 3 | 2 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.50 |