| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 74 | 20 | 20 | 5 | 8 | 6.31 | .361 | 1.67 | 11.2 | 3.9 | 4.8 | 107.0 | 133 | 80 | 75 | 16 | 46 | 57 | 0 | 0 | 0 | 0 | 6 | 2 | 3 | 5.22 |
| SP | Wakefield, T.Wakefield, Tim # >> | 37 | 2003 | R | 35 | 20 | 20 | 5 | 10 | 4.76 | .323 | 1.41 | 9.2 | 3.6 | 5.2 | 107.2 | 109 | 61 | 57 | 13 | 43 | 62 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 4.68 |
| SP | Pennock, H.Pennock, Herb >> | 26 | 1920 | L | 32 | 20 | 19 | 2 | 10 | 6.68 | .360 | 1.66 | 10.4 | 4.6 | 5.2 | 91.2 | 105 | 69 | 68 | 24 | 47 | 53 | 0 | 1 | 0 | 0 | 7 | 3 | 2 | 6.91 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 67 | 0 | 4 | 3 | 3.42 | .298 | 1.26 | 9.3 | 2.1 | 10.8 | 81.2 | 84 | 32 | 31 | 12 | 19 | 97 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 3.27 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 29 | 2017 | R | 99 | 64 | 0 | 7 | 2 | 3.05 | .246 | 0.98 | 5.8 | 3.1 | 11.5 | 76.2 | 49 | 27 | 26 | 7 | 26 | 97 | 0 | 2 | 2 | 0 | 0 | 0 | 4 | 2.67 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 69 | 0 | 2 | 2 | 4.88 | .308 | 1.28 | 7.9 | 3.8 | 10.0 | 55.1 | 48 | 30 | 30 | 7 | 23 | 61 | 0 | 5 | 2 | 0 | 0 | 3 | 5 | 3.85 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 29 | 2009 | R | 37 | 58 | 0 | 2 | 1 | 4.84 | .319 | 1.39 | 8.9 | 3.6 | 9.3 | 67.0 | 66 | 39 | 36 | 5 | 27 | 69 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 3.16 |
| RP | Fornieles, M.Fornieles, Mike >> | 28 | 1960 | R | 27 | 50 | 0 | 6 | 1 | 2.85 | .311 | 1.34 | 8.5 | 3.7 | 5.0 | 66.1 | 62 | 22 | 21 | 3 | 27 | 37 | 0 | 2 | 1 | 0 | 0 | 1 | 4 | 3.74 |