| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 14 | 14 | 6 | 6 | 3.31 | .272 | 1.10 | 7.8 | 2.2 | 7.9 | 111.1 | 96 | 41 | 41 | 8 | 27 | 98 | 6 | 0 | 0 | 1 | 7 | 2 | 1 | 2.95 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 14 | 14 | 5 | 3 | 3.50 | .275 | 1.14 | 6.9 | 3.3 | 5.4 | 103.0 | 79 | 46 | 40 | 8 | 38 | 62 | 1 | 0 | 0 | 0 | 10 | 0 | 3 | 3.91 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 14 | 14 | 4 | 8 | 5.34 | .336 | 1.51 | 10.7 | 2.9 | 6.4 | 94.1 | 112 | 57 | 56 | 14 | 30 | 67 | 2 | 0 | 0 | 0 | 5 | 1 | 0 | 4.50 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 13 | 13 | 7 | 5 | 3.98 | .278 | 1.14 | 7.4 | 2.9 | 6.7 | 92.2 | 76 | 41 | 41 | 9 | 30 | 68 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 3.80 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 27 | 0 | 2 | 2 | 0.95 | .241 | 0.92 | 5.8 | 2.6 | 9.0 | 28.1 | 18 | 5 | 3 | 0 | 8 | 28 | 0 | 21 | 1 | 0 | 0 | 1 | 0 | 1.96 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 33 | 0 | 3 | 2 | 3.52 | .281 | 1.13 | 7.0 | 3.1 | 10.6 | 23.0 | 18 | 9 | 9 | 2 | 8 | 27 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.96 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 38 | 0 | 1 | 0 | 2.10 | .214 | 0.82 | 6.1 | 1.4 | 7.6 | 25.2 | 17 | 6 | 6 | 2 | 4 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.84 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 10 | 0 | 2 | 0 | 2.45 | .241 | 0.95 | 7.7 | 1.3 | 7.7 | 7.1 | 6 | 2 | 2 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.71 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 7 | 0 | 0 | 0 | 4.33 | .296 | 1.26 | 8.0 | 3.3 | 8.7 | 27.0 | 24 | 13 | 13 | 2 | 10 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.15 |