| SP | Johnson, W.Johnson, Walter $ >> | 26 | 1913 | R | 95 | 13 | 13 | 5 | 3 | 2.85 | .258 | 1.04 | 7.2 | 2.2 | 3.9 | 98.0 | 78 | 33 | 31 | 4 | 24 | 42 | 6 | 0 | 0 | 2 | 10 | 0 | 2 | 3.41 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 13 | 13 | 6 | 3 | 3.33 | .266 | 1.06 | 7.7 | 2.0 | 10.4 | 83.2 | 71 | 33 | 31 | 9 | 18 | 96 | 1 | 0 | 0 | 0 | 8 | 2 | 2 | 2.82 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 13 | 13 | 9 | 1 | 2.61 | .285 | 1.15 | 5.9 | 4.6 | 9.3 | 89.2 | 58 | 27 | 26 | 4 | 45 | 92 | 0 | 0 | 0 | 0 | 10 | 4 | 2 | 3.17 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 13 | 13 | 3 | 7 | 4.39 | .305 | 1.32 | 9.1 | 2.7 | 8.1 | 82.0 | 83 | 44 | 40 | 10 | 25 | 74 | 1 | 0 | 0 | 0 | 8 | 0 | 3 | 3.70 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 12 | 12 | 5 | 4 | 3.30 | .302 | 1.25 | 7.5 | 3.9 | 5.9 | 84.2 | 70 | 32 | 31 | 4 | 36 | 55 | 3 | 0 | 0 | 2 | 7 | 4 | 3 | 3.74 |
| RP | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 98 | 39 | 0 | 2 | 2 | 3.54 | .299 | 1.28 | 7.2 | 4.5 | 7.7 | 20.1 | 16 | 10 | 8 | 3 | 10 | 17 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 4.75 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 33 | 0 | 2 | 3 | 4.05 | .291 | 1.23 | 7.9 | 3.3 | 11.2 | 33.1 | 29 | 15 | 15 | 4 | 12 | 41 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.18 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 5 | 0 | 1 | 1 | 5.40 | .333 | 1.35 | 10.5 | 3.0 | 9.0 | 6.2 | 7 | 4 | 4 | 3 | 2 | 6 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 9.00 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 82 | 4 | 0 | 0 | 1 | 4.76 | .261 | 1.06 | 10.8 | 0.0 | 7.2 | 5.2 | 6 | 3 | 3 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 8 | 0 | 0 | 1 | 0.93 | .171 | 0.62 | 4.0 | 2.0 | 9.0 | 9.2 | 4 | 1 | 1 | 1 | 2 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.11 |