| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 24 | 24 | 9 | 5 | 3.79 | .272 | 1.12 | 7.2 | 3.0 | 8.9 | 161.2 | 128 | 72 | 68 | 25 | 53 | 160 | 0 | 0 | 0 | 0 | 15 | 0 | 2 | 4.02 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 24 | 24 | 10 | 9 | 3.32 | .268 | 1.09 | 6.8 | 3.0 | 7.3 | 179.0 | 135 | 67 | 66 | 19 | 60 | 145 | 3 | 0 | 0 | 0 | 17 | 2 | 4 | 3.80 |
| SP | Maddux, G.Maddux, Greg † $$ >> | 29 | 1995 | R | 89 | 25 | 25 | 11 | 8 | 3.68 | .277 | 1.13 | 7.6 | 2.6 | 4.7 | 186.0 | 158 | 82 | 76 | 14 | 53 | 97 | 4 | 0 | 0 | 1 | 15 | 3 | 4 | 3.84 |
| SP | Mathewson, C.Mathewson, Christy † $$ >> | 28 | 1908 | R | 82 | 25 | 25 | 13 | 5 | 2.64 | .270 | 1.10 | 8.1 | 1.8 | 5.1 | 194.0 | 175 | 65 | 57 | 15 | 38 | 109 | 9 | 0 | 0 | 4 | 15 | 2 | 2 | 3.50 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 77 | 0 | 7 | 0 | 1.99 | .225 | 0.87 | 4.5 | 3.4 | 8.8 | 58.2 | 29 | 13 | 13 | 3 | 22 | 57 | 0 | 2 | 4 | 0 | 0 | 0 | 3 | 2.84 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 58 | 0 | 4 | 1 | 4.07 | .308 | 1.34 | 8.4 | 3.8 | 8.4 | 48.2 | 45 | 25 | 22 | 5 | 20 | 45 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 3.73 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 38 | 0 | 4 | 2 | 3.21 | .272 | 1.10 | 6.0 | 3.9 | 10.1 | 42.0 | 28 | 16 | 15 | 4 | 18 | 47 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 3.36 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 31 | 0 | 1 | 3 | 1.73 | .278 | 1.13 | 4.5 | 5.8 | 6.0 | 36.1 | 18 | 8 | 7 | 3 | 23 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.75 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 50 | 0 | 2 | 5 | 3.06 | .281 | 1.17 | 6.9 | 3.6 | 7.7 | 47.0 | 36 | 18 | 16 | 4 | 19 | 40 | 0 | 33 | 3 | 0 | 0 | 0 | 2 | 3.62 |