| SP | Koufax, S.Koufax, Sandy $$ >> | 30 | 1965 | L | 97 | 14 | 14 | 8 | 4 | 4.34 | .321 | 1.33 | 8.5 | 3.6 | 7.3 | 101.2 | 95 | 51 | 49 | 13 | 40 | 82 | 4 | 0 | 0 | 1 | 7 | 9 | 1 | 4.50 |
| SP | Santana, J.Santana, Johan $ >> | 25 | 2004 | L | 86 | 14 | 14 | 4 | 5 | 3.95 | .301 | 1.25 | 8.6 | 2.7 | 9.0 | 84.1 | 80 | 45 | 37 | 12 | 25 | 84 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 3.89 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 14 | 14 | 7 | 4 | 3.30 | .270 | 1.07 | 7.9 | 1.8 | 5.3 | 106.1 | 93 | 41 | 39 | 14 | 21 | 63 | 3 | 0 | 0 | 1 | 10 | 4 | 3 | 4.24 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 13 | 13 | 3 | 6 | 6.28 | .355 | 1.64 | 10.7 | 4.2 | 9.8 | 81.2 | 96 | 61 | 57 | 18 | 38 | 88 | 1 | 0 | 0 | 0 | 4 | 1 | 3 | 5.16 |
| CL | Gagne, E.Gagne, Eric $$ >> | 27 | 2003 | R | 97 | 30 | 0 | 2 | 3 | 3.23 | .292 | 1.24 | 6.0 | 5.4 | 9.9 | 30.2 | 20 | 11 | 11 | 2 | 18 | 33 | 0 | 12 | 3 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 29 | 0 | 1 | 0 | 2.51 | .265 | 1.08 | 6.4 | 3.5 | 10.3 | 28.2 | 20 | 9 | 8 | 1 | 11 | 32 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.36 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 19 | 0 | 2 | 2 | 3.47 | .300 | 1.24 | 7.4 | 3.9 | 8.2 | 23.1 | 19 | 9 | 9 | 2 | 10 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.74 |