| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 26 | 26 | 13 | 6 | 4.11 | .289 | 1.20 | 8.2 | 2.6 | 8.5 | 184.0 | 167 | 88 | 84 | 17 | 53 | 174 | 2 | 0 | 0 | 1 | 13 | 4 | 3 | 3.24 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 26 | 26 | 13 | 8 | 3.88 | .300 | 1.25 | 8.2 | 3.0 | 8.1 | 167.0 | 152 | 72 | 72 | 19 | 56 | 151 | 0 | 0 | 0 | 0 | 16 | 7 | 4 | 3.80 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 25 | 25 | 11 | 9 | 5.49 | .332 | 1.49 | 10.3 | 3.1 | 4.5 | 175.1 | 200 | 115 | 107 | 30 | 61 | 88 | 3 | 0 | 0 | 0 | 11 | 1 | 3 | 5.29 |
| SP | Clemens, R.Clemens, Roger $ >> | 24 | 1986 | R | 69 | 25 | 25 | 11 | 6 | 5.42 | .341 | 1.51 | 10.0 | 3.6 | 4.9 | 172.2 | 192 | 108 | 104 | 22 | 69 | 94 | 3 | 0 | 0 | 0 | 9 | 7 | 7 | 4.90 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 56 | 0 | 6 | 5 | 4.48 | .351 | 1.56 | 8.7 | 5.4 | 8.7 | 62.1 | 60 | 32 | 31 | 7 | 37 | 60 | 0 | 2 | 2 | 0 | 0 | 4 | 0 | 4.52 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 99 | 64 | 0 | 2 | 7 | 3.06 | .300 | 1.28 | 7.6 | 4.1 | 10.1 | 64.2 | 54 | 24 | 22 | 4 | 29 | 72 | 0 | 39 | 5 | 0 | 0 | 0 | 2 | 2.92 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 39 | 0 | 0 | 2 | 3.02 | .309 | 1.34 | 7.5 | 4.8 | 9.0 | 41.2 | 34 | 17 | 14 | 1 | 22 | 41 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 2.93 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 36 | 0 | 2 | 2 | 4.34 | .300 | 1.29 | 6.8 | 4.9 | 5.6 | 37.1 | 28 | 18 | 18 | 2 | 20 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.08 |