| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 27 | 27 | 8 | 15 | 4.50 | .288 | 1.20 | 8.1 | 2.7 | 5.4 | 186.0 | 168 | 100 | 93 | 26 | 55 | 111 | 9 | 0 | 0 | 1 | 14 | 3 | 3 | 4.56 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 26 | 26 | 8 | 11 | 4.83 | .305 | 1.29 | 8.9 | 2.7 | 4.7 | 177.0 | 175 | 107 | 95 | 22 | 54 | 92 | 6 | 0 | 0 | 1 | 14 | 4 | 1 | 4.56 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 24 | 24 | 3 | 14 | 5.27 | .352 | 1.62 | 10.7 | 3.9 | 5.0 | 169.0 | 200 | 116 | 99 | 26 | 74 | 94 | 5 | 0 | 0 | 0 | 8 | 2 | 4 | 5.24 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 60 | 0 | 1 | 4 | 3.65 | .293 | 1.24 | 7.9 | 3.3 | 7.1 | 81.1 | 71 | 35 | 33 | 9 | 30 | 64 | 0 | 6 | 3 | 0 | 0 | 0 | 2 | 3.98 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 50 | 0 | 5 | 4 | 4.27 | .298 | 1.25 | 6.7 | 4.6 | 8.1 | 59.0 | 44 | 31 | 28 | 9 | 30 | 53 | 0 | 1 | 4 | 0 | 0 | 1 | 0 | 4.76 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 1 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 0.0 | 9.0 | 0.0 | 1.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 20 | 0 | 2 | 2 | 4.20 | .302 | 1.27 | 9.0 | 2.4 | 4.8 | 30.0 | 30 | 14 | 14 | 3 | 8 | 16 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 4.13 |