| SP | Sale, C.Sale, Chris † # >> | 29 | 2018 | L | 98 | 20 | 20 | 11 | 6 | 2.84 | .241 | 0.95 | 6.5 | 2.1 | 8.5 | 133.1 | 96 | 43 | 42 | 12 | 31 | 125 | 1 | 0 | 0 | 1 | 15 | 0 | 2 | 2.99 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 19 | 19 | 8 | 8 | 4.22 | .296 | 1.23 | 8.5 | 2.7 | 4.7 | 132.1 | 124 | 64 | 62 | 13 | 39 | 69 | 2 | 0 | 0 | 0 | 10 | 4 | 2 | 4.21 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 18 | 18 | 6 | 8 | 4.61 | .302 | 1.27 | 7.7 | 3.7 | 4.1 | 123.0 | 105 | 65 | 63 | 17 | 51 | 56 | 1 | 0 | 0 | 0 | 9 | 4 | 4 | 5.23 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 18 | 18 | 8 | 4 | 5.09 | .337 | 1.50 | 9.3 | 4.2 | 8.0 | 104.1 | 108 | 62 | 59 | 16 | 49 | 92 | 0 | 0 | 0 | 0 | 10 | 2 | 1 | 4.70 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 52 | 0 | 4 | 4 | 2.86 | .267 | 1.06 | 6.2 | 3.4 | 8.0 | 91.1 | 63 | 32 | 29 | 6 | 34 | 81 | 0 | 14 | 3 | 0 | 0 | 3 | 0 | 3.30 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 47 | 0 | 4 | 0 | 2.02 | .230 | 0.90 | 6.7 | 1.4 | 7.4 | 58.0 | 43 | 13 | 13 | 5 | 9 | 48 | 0 | 8 | 1 | 0 | 0 | 0 | 2 | 2.93 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 27 | 0 | 0 | 0 | 4.91 | .307 | 1.33 | 6.2 | 5.9 | 9.6 | 29.1 | 20 | 16 | 16 | 4 | 19 | 31 | 0 | 4 | 2 | 0 | 0 | 0 | 5 | 4.62 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 61 | 21 | 0 | 3 | 0 | 2.63 | .250 | 1.00 | 8.3 | 0.8 | 6.0 | 24.0 | 22 | 8 | 7 | 3 | 2 | 16 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.54 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 20 | 0 | 1 | 3 | 3.38 | .289 | 1.22 | 9.0 | 2.0 | 5.9 | 32.0 | 32 | 12 | 12 | 4 | 7 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.97 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 6 | 0 | 1 | 1 | 9.72 | .342 | 1.56 | 9.0 | 5.6 | 4.5 | 8.1 | 8 | 9 | 9 | 5 | 5 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 12.00 |