| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 20 | 20 | 8 | 5 | 3.06 | .278 | 1.15 | 7.3 | 3.1 | 10.0 | 123.2 | 100 | 45 | 42 | 13 | 42 | 137 | 0 | 0 | 0 | 0 | 15 | 1 | 0 | 3.20 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 21 | 19 | 9 | 8 | 3.93 | .303 | 1.23 | 8.9 | 2.1 | 8.0 | 126.0 | 125 | 56 | 55 | 14 | 30 | 112 | 1 | 0 | 0 | 1 | 10 | 9 | 2 | 3.60 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 19 | 18 | 10 | 5 | 4.53 | .295 | 1.22 | 8.3 | 2.7 | 8.3 | 115.1 | 106 | 59 | 58 | 12 | 35 | 106 | 0 | 0 | 0 | 0 | 9 | 4 | 6 | 3.53 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 19 | 18 | 5 | 6 | 5.96 | .328 | 1.45 | 9.3 | 3.9 | 5.3 | 93.2 | 96 | 69 | 62 | 12 | 40 | 55 | 4 | 0 | 0 | 0 | 7 | 1 | 2 | 4.82 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 57 | 0 | 2 | 4 | 3.18 | .313 | 1.37 | 9.0 | 3.3 | 7.5 | 68.0 | 68 | 24 | 24 | 7 | 25 | 57 | 0 | 25 | 3 | 0 | 0 | 0 | 3 | 3.76 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 44 | 0 | 4 | 0 | 5.27 | .326 | 1.43 | 8.8 | 4.3 | 10.1 | 42.2 | 41 | 26 | 25 | 8 | 20 | 47 | 0 | 2 | 0 | 0 | 0 | 1 | 5 | 4.74 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 32 | 0 | 1 | 0 | 5.18 | .358 | 1.68 | 10.4 | 4.7 | 7.2 | 40.0 | 46 | 23 | 23 | 3 | 21 | 32 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.95 |