| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 20 | 20 | 7 | 11 | 4.58 | .310 | 1.33 | 9.5 | 2.4 | 6.8 | 116.0 | 123 | 59 | 59 | 12 | 31 | 88 | 0 | 0 | 0 | 0 | 11 | 2 | 7 | 3.68 |
| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 19 | 19 | 7 | 4 | 3.18 | .281 | 1.15 | 6.8 | 3.5 | 4.8 | 113.1 | 86 | 42 | 40 | 8 | 44 | 60 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 4.11 |
| SP | Richard, J.Richard, J.R. † $ >> | 30 | 1980 | R | 90 | 19 | 19 | 11 | 3 | 2.10 | .280 | 1.13 | 5.8 | 4.4 | 7.7 | 137.0 | 88 | 32 | 32 | 5 | 67 | 117 | 1 | 0 | 0 | 1 | 18 | 5 | 1 | 3.34 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 18 | 18 | 7 | 8 | 4.90 | .329 | 1.45 | 8.4 | 4.8 | 6.9 | 126.2 | 117 | 75 | 69 | 14 | 67 | 96 | 1 | 0 | 0 | 0 | 7 | 2 | 1 | 4.56 |
| RP | Chapman, A.Chapman, Aroldis $ >> | 26 | 2014 | L | 94 | 51 | 0 | 2 | 4 | 2.42 | .301 | 1.26 | 5.7 | 5.7 | 10.0 | 63.1 | 40 | 18 | 17 | 3 | 40 | 70 | 0 | 4 | 2 | 0 | 0 | 2 | 5 | 3.40 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 47 | 0 | 3 | 0 | 2.17 | .240 | 0.95 | 7.3 | 1.3 | 7.7 | 62.1 | 50 | 16 | 15 | 2 | 9 | 53 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 2.15 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 28 | 0 | 1 | 4 | 3.29 | .311 | 1.28 | 5.7 | 6.0 | 7.7 | 27.1 | 17 | 11 | 10 | 2 | 18 | 23 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 4.48 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 21 | 0 | 4 | 1 | 1.52 | .184 | 0.68 | 3.9 | 2.3 | 5.5 | 23.2 | 10 | 4 | 4 | 1 | 6 | 14 | 0 | 4 | 0 | 0 | 0 | 0 | 2 | 3.13 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 12 | 0 | 1 | 0 | 2.60 | .303 | 1.30 | 8.0 | 4.0 | 7.7 | 27.2 | 24 | 8 | 8 | 1 | 12 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.11 |