| SP | Marcum, S.Marcum, Shaun >> | 27 | 2008 | R | 92 | 3 | 3 | 1 | 0 | 3.86 | .300 | 1.29 | 6.4 | 5.1 | 4.7 | 21.0 | 15 | 9 | 9 | 4 | 12 | 11 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 6.14 |
| SP | Mussina, M.Mussina, Mike >> | 40 | 2008 | R | 50 | 3 | 3 | 0 | 2 | 5.71 | .316 | 1.27 | 10.1 | 1.6 | 4.2 | 17.1 | 19 | 11 | 11 | 4 | 3 | 8 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 6.00 |
| SP | Hernandez, F.Hernandez, Felix >> | 22 | 2008 | R | 31 | 3 | 3 | 0 | 2 | 5.89 | .313 | 1.36 | 10.0 | 2.5 | 5.0 | 18.1 | 20 | 12 | 12 | 5 | 5 | 10 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 6.33 |
| RP | Buchholz, T.Buchholz, Taylor >> | 27 | 2008 | R | 91 | 10 | 0 | 0 | 0 | 3.52 | .343 | 1.43 | 10.3 | 3.9 | 5.1 | 7.2 | 8 | 3 | 3 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.43 |
| RP | Street, H.Street, Huston >> | 25 | 2008 | R | 56 | 8 | 0 | 0 | 0 | 3.72 | .396 | 1.97 | 6.0 | 13.0 | 5.0 | 9.2 | 6 | 4 | 4 | 1 | 13 | 5 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 7.67 |
| RP | Hanrahan, J.Hanrahan, Joel >> | 27 | 2008 | R | 38 | 8 | 0 | 1 | 2 | 6.75 | .282 | 1.18 | 6.0 | 5.0 | 11.0 | 9.1 | 6 | 7 | 7 | 0 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.22 |
| SP | Bannister, B.Bannister, Brian >> | 27 | 2008 | R | 5 | 1 | 0 | 0 | 0 | 10.80 | .444 | 2.40 | 27.0 | 9.0 | 0.0 | 1.2 | 3 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Moehler, B.Moehler, Brian >> | 37 | 2008 | R | 18 | 5 | 0 | 1 | 0 | 2.70 | .231 | 0.90 | 7.5 | 1.5 | 9.0 | 6.2 | 5 | 2 | 2 | 1 | 1 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |