| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 98 | 4 | 4 | 3 | 0 | 1.31 | .248 | 0.96 | 6.6 | 2.1 | 6.9 | 34.1 | 25 | 7 | 5 | 3 | 8 | 26 | 2 | 0 | 0 | 1 | 4 | 1 | 0 | 3.41 |
| SP | Slowey, K.Slowey, Kevin >> | 24 | 2008 | R | 69 | 4 | 4 | 1 | 0 | 4.98 | .330 | 1.48 | 10.3 | 3.4 | 4.7 | 21.2 | 24 | 12 | 12 | 4 | 8 | 11 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.57 |
| SP | Rodriguez, W.Rodriguez, Wandy >> | 29 | 2008 | L | 44 | 4 | 4 | 1 | 1 | 4.35 | .326 | 1.40 | 11.3 | 1.8 | 7.2 | 20.2 | 25 | 14 | 10 | 3 | 4 | 16 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.10 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 98 | 9 | 0 | 0 | 0 | 1.38 | .235 | 0.92 | 4.2 | 4.2 | 8.3 | 13.0 | 6 | 2 | 2 | 2 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.54 |
| RP | Affeldt, J.Affeldt, Jeremy >> | 29 | 2008 | L | 30 | 9 | 0 | 1 | 0 | 1.64 | .250 | 0.91 | 7.4 | 0.8 | 8.2 | 11.0 | 9 | 2 | 2 | 0 | 1 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1.73 |
| SP | Hernandez, F.Hernandez, Felix >> | 22 | 2008 | R | 31 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Buehrle, M.Buehrle, Mark >> | 29 | 2008 | L | 21 | 6 | 0 | 1 | 2 | 11.88 | .500 | 3.00 | 21.4 | 6.8 | 3.4 | 8.1 | 19 | 11 | 11 | 1 | 6 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.13 |