| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 98 | 3 | 3 | 0 | 2 | 6.75 | .360 | 1.69 | 12.4 | 2.8 | 7.3 | 16.0 | 22 | 12 | 12 | 3 | 5 | 13 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.75 |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 88 | 3 | 3 | 1 | 1 | 3.00 | .308 | 1.33 | 9.0 | 3.0 | 6.4 | 21.0 | 21 | 7 | 7 | 0 | 7 | 15 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2.57 |
| SP | Guthrie, J.Guthrie, Jeremy >> | 29 | 2008 | R | 64 | 3 | 3 | 3 | 0 | 3.80 | .256 | 1.03 | 6.4 | 3.0 | 4.3 | 21.1 | 15 | 9 | 9 | 2 | 7 | 10 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 4.29 |
| SP | Greinke, Z.Greinke, Zack >> | 25 | 2008 | R | 53 | 2 | 2 | 0 | 1 | 6.23 | .366 | 1.73 | 13.5 | 3.4 | 4.5 | 8.2 | 12 | 6 | 6 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.75 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 98 | 11 | 0 | 0 | 0 | 1.54 | .271 | 1.11 | 4.9 | 5.7 | 9.0 | 11.2 | 6 | 2 | 2 | 1 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.09 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 84 | 10 | 0 | 0 | 2 | 6.52 | .370 | 1.55 | 10.0 | 5.0 | 7.0 | 9.2 | 10 | 7 | 7 | 0 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.78 |
| RP | Dotel, O.Dotel, Octavio >> | 35 | 2008 | R | 69 | 9 | 0 | 1 | 0 | 2.79 | .293 | 1.24 | 7.0 | 5.0 | 10.0 | 9.2 | 7 | 3 | 3 | 1 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.89 |
| RP | Ramirez, E.Ramirez, Edwar >> | 27 | 2008 | R | 58 | 6 | 0 | 0 | 0 | 5.40 | .423 | 2.00 | 12.6 | 5.4 | 12.6 | 5.0 | 7 | 3 | 3 | 0 | 3 | 7 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.60 |