| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 12 | 12 | 3 | 5 | 3.27 | .279 | 1.14 | 8.6 | 1.8 | 7.4 | 82.2 | 78 | 35 | 30 | 11 | 16 | 67 | 2 | 0 | 0 | 1 | 8 | 2 | 1 | 3.77 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 12 | 12 | 4 | 6 | 6.00 | .357 | 1.65 | 10.8 | 4.1 | 4.2 | 66.0 | 79 | 45 | 44 | 12 | 30 | 31 | 1 | 0 | 0 | 1 | 3 | 1 | 0 | 5.83 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 12 | 12 | 6 | 2 | 2.52 | .264 | 1.05 | 7.0 | 2.5 | 5.7 | 89.1 | 69 | 26 | 25 | 6 | 25 | 56 | 4 | 0 | 0 | 1 | 10 | 2 | 0 | 3.53 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 28 | 0 | 3 | 3 | 3.19 | .290 | 1.23 | 9.0 | 2.0 | 8.1 | 31.0 | 31 | 13 | 11 | 3 | 7 | 28 | 0 | 10 | 3 | 0 | 0 | 0 | 0 | 3.13 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 33 | 0 | 0 | 1 | 4.23 | .294 | 1.25 | 7.3 | 4.0 | 9.2 | 38.1 | 31 | 19 | 18 | 4 | 17 | 39 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.66 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 30 | 0 | 3 | 0 | 3.19 | .316 | 1.39 | 6.7 | 5.8 | 10.7 | 31.0 | 23 | 11 | 11 | 1 | 20 | 37 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.97 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 24 | 0 | 4 | 0 | 6.23 | .358 | 1.64 | 8.7 | 6.4 | 8.7 | 34.2 | 33 | 29 | 24 | 2 | 24 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.03 |