| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 26 | 26 | 7 | 12 | 5.78 | .324 | 1.42 | 10.3 | 2.6 | 8.5 | 141.2 | 161 | 94 | 91 | 25 | 40 | 133 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 4.33 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 26 | 25 | 10 | 8 | 4.26 | .301 | 1.26 | 8.0 | 3.5 | 4.8 | 164.2 | 145 | 81 | 78 | 15 | 63 | 87 | 4 | 0 | 0 | 0 | 12 | 5 | 1 | 4.37 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 25 | 25 | 8 | 8 | 4.56 | .308 | 1.32 | 9.2 | 2.7 | 4.1 | 154.0 | 157 | 83 | 78 | 16 | 47 | 70 | 4 | 0 | 0 | 1 | 12 | 2 | 3 | 4.40 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 63 | 0 | 8 | 6 | 3.82 | .309 | 1.31 | 7.1 | 4.8 | 9.5 | 75.1 | 59 | 36 | 32 | 6 | 40 | 79 | 0 | 1 | 1 | 0 | 0 | 2 | 7 | 3.61 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 47 | 0 | 1 | 2 | 4.50 | .320 | 1.41 | 9.0 | 3.7 | 8.2 | 46.0 | 46 | 25 | 23 | 9 | 19 | 42 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 4.96 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 38 | 0 | 3 | 1 | 2.85 | .328 | 1.46 | 8.3 | 4.8 | 8.6 | 41.0 | 38 | 14 | 13 | 7 | 22 | 39 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.93 |
| SU | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 51 | 0 | 1 | 2 | 3.09 | .317 | 1.39 | 9.2 | 3.4 | 7.0 | 55.1 | 56 | 23 | 19 | 2 | 21 | 43 | 0 | 6 | 2 | 0 | 0 | 0 | 2 | 3.05 |
| CL | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 99 | 43 | 0 | 3 | 3 | 4.67 | .338 | 1.49 | 9.4 | 4.1 | 7.6 | 44.1 | 46 | 29 | 23 | 3 | 20 | 37 | 0 | 20 | 5 | 0 | 0 | 2 | 0 | 3.70 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 24 | 0 | 4 | 3 | 4.99 | .327 | 1.43 | 10.1 | 2.8 | 7.2 | 97.1 | 109 | 56 | 54 | 13 | 30 | 78 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 4.15 |