| SP | Bauer, T.Bauer, Trevor † >> | 27 | 2018 | R | 93 | 25 | 25 | 11 | 7 | 3.43 | .295 | 1.24 | 8.2 | 3.0 | 10.0 | 155.0 | 141 | 61 | 59 | 15 | 51 | 173 | 1 | 0 | 0 | 1 | 16 | 3 | 6 | 3.07 |
| SP | Kluber, C.Kluber, Corey >> | 32 | 2018 | R | 91 | 24 | 24 | 8 | 11 | 4.78 | .321 | 1.38 | 10.2 | 2.2 | 10.0 | 156.1 | 177 | 83 | 83 | 20 | 38 | 173 | 1 | 0 | 0 | 0 | 12 | 7 | 3 | 3.31 |
| SP | Kershaw, C.Kershaw, Clayton >> | 30 | 2018 | L | 88 | 23 | 23 | 11 | 6 | 3.04 | .260 | 1.04 | 7.3 | 2.1 | 7.8 | 160.0 | 129 | 54 | 54 | 18 | 37 | 138 | 0 | 0 | 0 | 0 | 19 | 3 | 5 | 3.49 |
| SP | Severino, L.Severino, Luis >> | 24 | 2018 | R | 74 | 23 | 23 | 10 | 9 | 5.39 | .337 | 1.50 | 10.4 | 3.0 | 10.4 | 127.0 | 147 | 77 | 76 | 18 | 43 | 147 | 0 | 0 | 0 | 0 | 9 | 4 | 5 | 3.64 |
| SP | Porcello, R.Porcello, Rick >> | 29 | 2018 | R | 68 | 23 | 23 | 3 | 13 | 7.01 | .363 | 1.68 | 11.6 | 3.6 | 9.2 | 119.1 | 154 | 97 | 93 | 29 | 47 | 121 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 5.39 |
| RP | Kelley, S.Kelley, Shawn >> | 34 | 2018 | R | 92 | 67 | 0 | 3 | 4 | 2.87 | .279 | 1.09 | 7.7 | 2.1 | 9.3 | 69.0 | 59 | 23 | 22 | 6 | 16 | 71 | 0 | 5 | 2 | 0 | 0 | 5 | 3 | 2.99 |
| RP | Rogers, T.Rogers, Taylor >> | 27 | 2018 | L | 90 | 60 | 0 | 2 | 2 | 2.40 | .271 | 0.99 | 6.1 | 2.9 | 13.6 | 41.1 | 28 | 11 | 11 | 4 | 13 | 62 | 0 | 7 | 0 | 0 | 0 | 5 | 0 | 2.56 |
| RP | Morrow, B.Morrow, Brandon >> | 34 | 2018 | R | 69 | 27 | 0 | 2 | 0 | 2.79 | .287 | 1.14 | 8.1 | 2.2 | 10.9 | 29.0 | 26 | 9 | 9 | 3 | 7 | 35 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 2.86 |
| SP | Taillon, J.Taillon, Jameson >> | 26 | 2018 | R | 65 | 14 | 0 | 1 | 2 | 6.07 | .362 | 1.69 | 10.8 | 4.5 | 7.2 | 56.1 | 67 | 39 | 38 | 6 | 28 | 45 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.34 |