| SP | Scherzer, M.Scherzer, Max >> | 34 | 2018 | R | 100 | 10 | 10 | 3 | 4 | 3.66 | .284 | 1.16 | 7.1 | 3.4 | 11.2 | 66.1 | 52 | 27 | 27 | 5 | 25 | 82 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 2.73 |
| SP | Paxton, J.Paxton, James >> | 29 | 2018 | L | 89 | 10 | 10 | 6 | 2 | 2.93 | .272 | 1.05 | 6.7 | 2.8 | 10.3 | 55.1 | 41 | 18 | 18 | 5 | 17 | 63 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 3.04 |
| SP | Greinke, Z.Greinke, Zack # >> | 35 | 2018 | R | 84 | 10 | 10 | 3 | 6 | 4.87 | .309 | 1.33 | 9.0 | 3.0 | 10.4 | 57.1 | 57 | 31 | 31 | 8 | 19 | 66 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 3.56 |
| SP | Kluber, C.Kluber, Corey >> | 32 | 2018 | R | 91 | 11 | 10 | 5 | 4 | 4.34 | .301 | 1.24 | 8.7 | 2.5 | 10.6 | 58.0 | 56 | 28 | 28 | 8 | 16 | 68 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 3.43 |
| SP | Rodriguez, D.Rodriguez, Dereck >> | 26 | 2018 | R | 76 | 10 | 10 | 0 | 4 | 9.30 | .374 | 1.74 | 11.5 | 4.4 | 6.5 | 39.2 | 50 | 41 | 41 | 12 | 19 | 28 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 7.18 |
| CL | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 96 | 18 | 0 | 1 | 3 | 6.00 | .308 | 1.28 | 8.5 | 3.0 | 11.5 | 18.0 | 17 | 12 | 12 | 4 | 6 | 23 | 0 | 10 | 2 | 0 | 0 | 1 | 0 | 4.50 |
| RP | Jeffress, J.Jeffress, Jeremy >> | 30 | 2018 | R | 91 | 28 | 0 | 3 | 0 | 2.78 | .291 | 1.18 | 8.7 | 2.1 | 9.0 | 35.2 | 34 | 11 | 11 | 2 | 8 | 35 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 2.60 |
| RP | Fields, J.Fields, Josh >> | 32 | 2018 | R | 87 | 25 | 0 | 0 | 0 | 0.59 | .229 | 0.82 | 6.0 | 1.5 | 7.2 | 30.1 | 20 | 3 | 2 | 0 | 5 | 24 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2.10 |
| RP | Jansen, K.Jansen, Kenley >> | 30 | 2018 | R | 85 | 17 | 0 | 2 | 1 | 0.77 | .146 | 0.51 | 2.7 | 2.0 | 9.0 | 23.1 | 7 | 3 | 2 | 0 | 5 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.65 |
| RP | Rodriguez, R.Rodriguez, Richard >> | 28 | 2018 | R | 77 | 9 | 0 | 0 | 0 | 3.09 | .239 | 0.86 | 5.7 | 2.5 | 9.0 | 11.2 | 7 | 4 | 4 | 3 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.64 |
| RP | Hughes, J.Hughes, Jared >> | 32 | 2018 | R | 76 | 5 | 0 | 0 | 0 | 9.00 | .368 | 1.75 | 13.5 | 2.3 | 2.3 | 4.0 | 6 | 4 | 4 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.25 |
| RP | Hirano, Y.Hirano, Yoshihisa >> | 34 | 2018 | R | 70 | 10 | 0 | 1 | 0 | 2.53 | .319 | 1.31 | 9.9 | 2.7 | 8.1 | 10.2 | 11 | 3 | 3 | 1 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.70 |
| SP | Wacha, M.Wacha, Michael >> | 26 | 2018 | R | 70 | 5 | 0 | 2 | 0 | 2.92 | .288 | 1.18 | 7.5 | 3.4 | 10.9 | 24.2 | 20 | 9 | 8 | 2 | 9 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.92 |