| SP | Verlander, J.Verlander, Justin † >> | 35 | 2018 | R | 98 | 34 | 34 | 13 | 13 | 3.42 | .289 | 1.18 | 8.2 | 2.5 | 10.0 | 229.0 | 208 | 88 | 87 | 20 | 63 | 254 | 3 | 0 | 0 | 3 | 22 | 8 | 3 | 2.85 |
| SP | Teheran, J.Teheran, Julio >> | 27 | 2018 | R | 83 | 33 | 33 | 6 | 13 | 3.69 | .302 | 1.29 | 7.6 | 4.1 | 8.0 | 202.2 | 170 | 90 | 83 | 22 | 92 | 179 | 0 | 0 | 0 | 0 | 15 | 1 | 2 | 4.02 |
| SP | Porcello, R.Porcello, Rick # >> | 29 | 2018 | R | 68 | 32 | 32 | 14 | 12 | 5.05 | .329 | 1.39 | 9.1 | 3.5 | 7.9 | 180.0 | 181 | 101 | 101 | 21 | 70 | 158 | 0 | 0 | 0 | 0 | 11 | 14 | 3 | 4.16 |
| SP | Heaney, A.Heaney, Andrew >> | 27 | 2018 | L | 60 | 32 | 32 | 11 | 12 | 4.47 | .324 | 1.40 | 9.5 | 3.2 | 9.0 | 199.1 | 210 | 109 | 99 | 24 | 70 | 200 | 1 | 0 | 0 | 0 | 18 | 7 | 10 | 3.72 |
| SP | Castillo, L.Castillo, Luis >> | 25 | 2018 | R | 58 | 32 | 31 | 7 | 13 | 5.82 | .331 | 1.46 | 9.7 | 3.4 | 7.4 | 167.0 | 180 | 111 | 108 | 26 | 63 | 138 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 4.59 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 97 | 100 | 0 | 5 | 3 | 2.92 | .294 | 1.21 | 6.0 | 4.9 | 10.4 | 132.1 | 88 | 43 | 43 | 8 | 72 | 153 | 0 | 6 | 2 | 0 | 0 | 5 | 1 | 3.22 |
| RP | Moronta, R.Moronta, Reyes >> | 25 | 2018 | R | 84 | 94 | 0 | 5 | 7 | 3.79 | .321 | 1.34 | 6.2 | 5.9 | 11.0 | 118.2 | 81 | 51 | 50 | 6 | 78 | 144 | 0 | 9 | 6 | 0 | 0 | 9 | 9 | 3.43 |
| RP | Crick, K.Crick, Kyle # >> | 25 | 2018 | R | 69 | 88 | 0 | 8 | 9 | 5.25 | .356 | 1.60 | 9.8 | 4.7 | 9.8 | 96.0 | 104 | 60 | 56 | 13 | 50 | 104 | 0 | 5 | 11 | 0 | 0 | 5 | 10 | 4.31 |
| RP | Edwards, C.Edwards, Carl >> | 26 | 2018 | R | 60 | 72 | 0 | 4 | 4 | 3.77 | .332 | 1.47 | 8.5 | 4.8 | 11.5 | 71.2 | 67 | 30 | 30 | 5 | 38 | 91 | 0 | 9 | 1 | 0 | 0 | 2 | 3 | 3.04 |
| RP | Britton, Z.Britton, Zach >> | 30 | 2018 | L | 53 | 53 | 0 | 3 | 0 | 2.01 | .277 | 1.10 | 5.7 | 4.4 | 7.0 | 62.2 | 39 | 16 | 14 | 3 | 30 | 48 | 0 | 5 | 3 | 0 | 0 | 3 | 7 | 3.68 |