| SP | Sanchez, A.Sanchez, Anibal >> | 34 | 2018 | R | 90 | 23 | 23 | 9 | 8 | 3.54 | .312 | 1.33 | 8.4 | 3.6 | 8.5 | 129.2 | 120 | 58 | 51 | 15 | 52 | 122 | 1 | 0 | 0 | 1 | 11 | 4 | 6 | 3.92 |
| SP | Clevinger, M.Clevinger, Mike >> | 27 | 2018 | R | 81 | 23 | 23 | 3 | 9 | 4.32 | .336 | 1.50 | 9.5 | 4.0 | 9.3 | 141.2 | 149 | 79 | 68 | 23 | 63 | 145 | 0 | 0 | 0 | 0 | 14 | 3 | 3 | 4.47 |
| SP | Eovaldi, N.Eovaldi, Nathan >> | 28 | 2018 | R | 71 | 23 | 23 | 5 | 6 | 5.40 | .327 | 1.42 | 10.5 | 2.4 | 7.3 | 116.2 | 135 | 72 | 70 | 28 | 31 | 94 | 0 | 0 | 0 | 0 | 3 | 4 | 5 | 5.42 |
| SP | Chacin, J.Chacin, Jhoulys >> | 30 | 2018 | R | 78 | 24 | 23 | 7 | 7 | 5.12 | .318 | 1.35 | 8.0 | 4.1 | 7.6 | 130.0 | 116 | 76 | 74 | 22 | 59 | 110 | 0 | 1 | 0 | 0 | 4 | 7 | 2 | 5.03 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 100 | 55 | 0 | 6 | 3 | 1.54 | .278 | 1.14 | 5.3 | 5.0 | 11.4 | 76.0 | 45 | 14 | 13 | 4 | 42 | 96 | 0 | 17 | 1 | 0 | 0 | 1 | 0 | 2.86 |
| SU | Jeffress, J.Jeffress, Jeremy >> | 30 | 2018 | R | 91 | 61 | 0 | 5 | 3 | 6.32 | .363 | 1.66 | 11.3 | 3.8 | 10.2 | 62.2 | 78 | 45 | 44 | 16 | 26 | 70 | 0 | 2 | 4 | 0 | 0 | 3 | 2 | 5.50 |
| RP | Peacock, B.Peacock, Brad >> | 30 | 2018 | R | 65 | 56 | 0 | 3 | 3 | 4.65 | .313 | 1.32 | 8.9 | 3.1 | 10.6 | 69.2 | 68 | 36 | 36 | 12 | 24 | 81 | 0 | 0 | 3 | 0 | 0 | 3 | 1 | 4.09 |