| SP | Arrieta, J.Arrieta, Jake # >> | 33 | 2014 | R | 79 | 14 | 14 | 4 | 9 | 5.79 | .341 | 1.53 | 9.9 | 4.0 | 7.8 | 74.2 | 81 | 51 | 48 | 13 | 33 | 64 | 0 | 0 | 0 | 0 | 6 | 2 | 4 | 4.97 |
| SP | Samardzija, J.Samardzija, Jeff >> | 28 | 2011 | R | 61 | 13 | 13 | 3 | 5 | 4.79 | .363 | 1.68 | 10.1 | 5.1 | 9.4 | 71.1 | 80 | 39 | 38 | 9 | 40 | 74 | 0 | 0 | 0 | 0 | 6 | 2 | 7 | 4.34 |
| RP | Benoit, J.Benoit, Joaquin >> | 34 | 2010 | R | 90 | 35 | 0 | 0 | 2 | 2.23 | .239 | 0.92 | 4.7 | 3.6 | 10.1 | 40.1 | 21 | 10 | 10 | 2 | 16 | 45 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.68 |
| RP | Dominguez, S.Dominguez, Seranthony >> | 32 | 2018 | R | 89 | 30 | 0 | 3 | 3 | 7.76 | .361 | 1.63 | 10.2 | 4.6 | 9.3 | 31.1 | 35 | 27 | 27 | 5 | 16 | 32 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 4.77 |
| RP | Hoover, J.Hoover, J.J. >> | 27 | 2012 | R | 71 | 22 | 0 | 1 | 1 | 1.05 | .252 | 0.97 | 5.0 | 4.0 | 12.6 | 25.2 | 14 | 3 | 3 | 0 | 11 | 35 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1.64 |
| RP | Carpenter, D.Carpenter, David >> | 31 | 2013 | R | 43 | 15 | 0 | 1 | 1 | 1.93 | .236 | 0.93 | 5.8 | 2.6 | 9.6 | 14.0 | 9 | 3 | 3 | 1 | 4 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.64 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 33 | 2011 | R | 25 | 18 | 0 | 1 | 1 | 3.68 | .290 | 1.09 | 9.0 | 1.3 | 9.0 | 14.2 | 14 | 6 | 6 | 1 | 2 | 14 | 0 | 12 | 2 | 0 | 0 | 2 | 1 | 2.79 |
| SP | Padilla, V.Padilla, Vicente >> | 34 | 2010 | R | 33 | 12 | 0 | 1 | 1 | 3.00 | .330 | 1.42 | 9.4 | 3.4 | 6.4 | 48.0 | 50 | 21 | 16 | 3 | 18 | 34 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 3.71 |