| SP | Hendricks, K.Hendricks, Kyle # >> | 33 | 2016 | R | 89 | 14 | 14 | 4 | 7 | 5.40 | .328 | 1.42 | 9.9 | 3.0 | 7.8 | 91.2 | 100 | 56 | 55 | 20 | 30 | 79 | 1 | 0 | 0 | 0 | 5 | 4 | 0 | 5.24 |
| SP | Beachy, B.Beachy, Brandon >> | 30 | 2013 | R | 87 | 14 | 14 | 4 | 5 | 5.43 | .327 | 1.40 | 10.0 | 2.7 | 8.4 | 56.1 | 62 | 34 | 34 | 14 | 17 | 52 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 5.46 |
| SP | Alvarez, H.Alvarez, Henderson # >> | 27 | 2013 | R | 71 | 14 | 13 | 3 | 6 | 5.40 | .310 | 1.33 | 8.5 | 3.4 | 6.9 | 55.0 | 52 | 34 | 33 | 7 | 21 | 42 | 0 | 0 | 1 | 0 | 3 | 1 | 1 | 4.33 |
| SP | Strasburg, S.Strasburg, Stephen >> | 22 | 2010 | R | 50 | 13 | 13 | 3 | 4 | 4.73 | .298 | 1.26 | 9.0 | 2.4 | 10.5 | 53.1 | 53 | 29 | 28 | 10 | 14 | 62 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.96 |
| RP | Familia, J.Familia, Jeurys >> | 31 | 2015 | R | 65 | 36 | 0 | 2 | 0 | 3.83 | .260 | 1.05 | 8.0 | 1.6 | 9.2 | 44.2 | 39 | 21 | 19 | 7 | 8 | 45 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.57 |
| RP | Thornburg, T.Thornburg, Tyler >> | 34 | 2016 | R | 54 | 26 | 0 | 1 | 0 | 4.35 | .331 | 1.48 | 9.9 | 3.5 | 10.5 | 31.0 | 34 | 16 | 15 | 6 | 12 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.35 |
| RP | Vargas, C.Vargas, Claudio >> | 31 | 2009 | R | 53 | 24 | 0 | 1 | 0 | 2.25 | .250 | 0.96 | 5.8 | 2.9 | 6.8 | 28.0 | 18 | 7 | 7 | 4 | 9 | 21 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.43 |
| RP | Balfour, G.Balfour, Grant >> | 38 | 2012 | R | 38 | 17 | 0 | 1 | 2 | 2.12 | .271 | 1.12 | 6.9 | 3.2 | 5.3 | 17.0 | 13 | 6 | 4 | 3 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.18 |
| RP | Breslow, C.Breslow, Craig >> | 29 | 2009 | L | 29 | 36 | 0 | 3 | 2 | 4.20 | .291 | 1.20 | 5.7 | 5.1 | 5.4 | 30.0 | 19 | 18 | 14 | 2 | 17 | 18 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.47 |
| SP | Darvish, Y.Darvish, Yu >> | 22 | 2009 | R | 93 | 14 | 8 | 6 | 2 | 3.86 | .282 | 1.15 | 7.9 | 2.6 | 7.2 | 74.2 | 65 | 32 | 32 | 12 | 21 | 59 | 3 | 2 | 0 | 1 | 3 | 2 | 4 | 4.45 |
| CL | Edwards, C.Edwards, Carl >> | 31 | 2016 | R | 100 | 25 | 0 | 4 | 0 | 2.70 | .274 | 1.13 | 3.9 | 6.3 | 12.0 | 30.0 | 13 | 9 | 9 | 3 | 21 | 40 | 0 | 13 | 1 | 0 | 0 | 0 | 2 | 3.73 |