| SP | Verlander, J.Verlander, Justin >> | 30 | 2011 | R | 90 | 14 | 14 | 4 | 6 | 5.30 | .321 | 1.41 | 9.4 | 3.4 | 7.4 | 91.2 | 95 | 54 | 54 | 14 | 34 | 75 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 4.51 |
| SP | McHugh, C.McHugh, Collin >> | 32 | 2014 | R | 85 | 14 | 14 | 6 | 4 | 4.40 | .327 | 1.40 | 8.5 | 4.1 | 8.9 | 88.0 | 83 | 45 | 43 | 16 | 40 | 87 | 0 | 0 | 0 | 0 | 6 | 5 | 0 | 4.92 |
| SP | Keuchel, D.Keuchel, Dallas >> | 33 | 2015 | L | 81 | 14 | 14 | 6 | 6 | 5.00 | .304 | 1.27 | 9.4 | 2.1 | 7.5 | 86.1 | 90 | 50 | 48 | 21 | 20 | 72 | 1 | 0 | 0 | 0 | 6 | 3 | 3 | 5.30 |
| SP | Hamels, C.Hamels, Cole >> | 30 | 2011 | L | 70 | 9 | 8 | 2 | 3 | 6.80 | .355 | 1.61 | 10.3 | 4.2 | 6.6 | 49.0 | 56 | 38 | 37 | 11 | 23 | 36 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.98 |
| RP | Osuna, R.Osuna, Roberto >> | 30 | 2017 | R | 83 | 31 | 0 | 1 | 1 | 2.87 | .315 | 1.33 | 9.0 | 3.2 | 10.5 | 37.2 | 37 | 13 | 12 | 4 | 13 | 43 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.30 |
| RP | Gregerson, L.Gregerson, Luke >> | 27 | 2010 | R | 87 | 23 | 0 | 1 | 1 | 2.88 | .235 | 0.92 | 5.8 | 2.5 | 9.7 | 25.0 | 16 | 8 | 8 | 2 | 7 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Devenski, C.Devenski, Chris >> | 32 | 2016 | R | 65 | 10 | 0 | 0 | 1 | 6.23 | .350 | 1.62 | 11.1 | 3.5 | 4.8 | 13.0 | 16 | 9 | 9 | 3 | 5 | 7 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 6.08 |
| RP | Storen, D.Storen, Drew >> | 25 | 2011 | R | 44 | 6 | 0 | 0 | 1 | 6.75 | .355 | 1.65 | 12.0 | 4.5 | 12.0 | 6.2 | 8 | 5 | 5 | 0 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.83 |
| RP | Guzman, A.Guzman, Angel >> | 28 | 2009 | R | 40 | 2 | 0 | 0 | 0 | 8.10 | .375 | 1.80 | 15.0 | 3.0 | 9.0 | 3.1 | 5 | 3 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.33 |
| RP | Valverde, J.Valverde, Jose >> | 30 | 2009 | R | 25 | 11 | 0 | 0 | 0 | 0.87 | .295 | 1.26 | 7.2 | 4.5 | 6.3 | 10.1 | 8 | 3 | 1 | 2 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.70 |
| SP | Valdez, F.Valdez, Framber >> | 33 | 2018 | L | 54 | 10 | 0 | 1 | 1 | 4.79 | .299 | 1.28 | 6.1 | 5.5 | 9.9 | 41.1 | 28 | 22 | 22 | 8 | 25 | 45 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 5.17 |