| SP | Keuchel, D.Keuchel, Dallas >> | 30 | 2015 | L | 91 | 6 | 6 | 3 | 1 | 4.98 | .305 | 1.32 | 8.6 | 3.3 | 9.0 | 43.1 | 41 | 28 | 24 | 5 | 16 | 43 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.63 |
| SP | McHugh, C.McHugh, Collin >> | 29 | 2014 | R | 92 | 5 | 5 | 2 | 2 | 3.34 | .265 | 1.02 | 7.6 | 1.7 | 9.3 | 32.1 | 27 | 12 | 12 | 2 | 6 | 33 | 1 | 0 | 0 | 1 | 3 | 2 | 0 | 2.50 |
| SP | Valdez, F.Valdez, Framber >> | 30 | 2018 | L | 88 | 5 | 5 | 2 | 0 | 4.21 | .319 | 1.36 | 7.6 | 5.0 | 9.0 | 25.2 | 21 | 12 | 12 | 3 | 14 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4.36 |
| SP | Verlander, J.Verlander, Justin >> | 29 | 2012 | R | 76 | 5 | 5 | 3 | 2 | 3.50 | .299 | 1.25 | 8.0 | 3.3 | 11.3 | 36.0 | 32 | 15 | 14 | 3 | 13 | 45 | 1 | 0 | 0 | 1 | 3 | 1 | 0 | 2.75 |
| RP | Osuna, R.Osuna, Roberto >> | 27 | 2017 | R | 90 | 14 | 0 | 1 | 0 | 1.13 | .250 | 1.00 | 6.8 | 2.3 | 9.0 | 16.0 | 12 | 3 | 2 | 2 | 4 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.38 |
| RP | Devenski, C.Devenski, Chris >> | 29 | 2016 | R | 79 | 10 | 0 | 1 | 0 | 3.27 | .267 | 1.09 | 7.4 | 2.5 | 8.2 | 11.0 | 9 | 4 | 4 | 0 | 3 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Gregerson, L.Gregerson, Luke >> | 30 | 2013 | R | 63 | 5 | 0 | 1 | 0 | 0.00 | .222 | 0.86 | 2.3 | 6.8 | 4.5 | 4.2 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.25 |
| SP | Hamels, C.Hamels, Cole >> | 29 | 2012 | L | 61 | 3 | 0 | 0 | 1 | 2.70 | .286 | 1.20 | 5.4 | 5.4 | 9.9 | 10.0 | 6 | 3 | 3 | 0 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Storen, D.Storen, Drew >> | 24 | 2012 | R | 62 | 2 | 0 | 0 | 1 | 9.00 | .250 | 1.00 | 9.0 | 0.0 | 0.0 | 1.0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |