| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 11 | 12 | 4.15 | .303 | 1.29 | 8.2 | 3.4 | 9.1 | 214.2 | 195 | 102 | 99 | 27 | 81 | 216 | 1 | 0 | 0 | 1 | 21 | 4 | 5 | 3.81 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 32 | 32 | 14 | 11 | 4.11 | .296 | 1.24 | 8.6 | 2.6 | 8.5 | 214.2 | 204 | 109 | 98 | 23 | 63 | 203 | 6 | 0 | 0 | 1 | 19 | 4 | 6 | 3.44 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 32 | 32 | 8 | 12 | 5.33 | .304 | 1.29 | 9.2 | 2.4 | 7.6 | 204.1 | 209 | 127 | 121 | 41 | 55 | 173 | 1 | 0 | 0 | 0 | 11 | 4 | 5 | 4.78 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 31 | 31 | 15 | 10 | 4.46 | .304 | 1.29 | 9.0 | 2.5 | 4.4 | 216.0 | 217 | 115 | 107 | 23 | 61 | 106 | 4 | 0 | 0 | 1 | 15 | 5 | 1 | 4.32 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 30 | 30 | 13 | 12 | 4.54 | .325 | 1.43 | 8.4 | 4.5 | 8.0 | 194.1 | 180 | 99 | 98 | 27 | 98 | 172 | 0 | 0 | 0 | 0 | 16 | 3 | 2 | 4.60 |
| RP | Nathan, J.Nathan, Joe $ >> | 32 | 2006 | R | 86 | 78 | 0 | 5 | 0 | 2.15 | .287 | 1.19 | 5.9 | 5.0 | 8.2 | 58.2 | 38 | 17 | 14 | 3 | 32 | 53 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 3.55 |
| CL | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 48 | 0 | 5 | 5 | 3.83 | .287 | 1.19 | 7.0 | 3.9 | 8.0 | 44.2 | 34 | 20 | 19 | 5 | 19 | 39 | 0 | 29 | 4 | 0 | 0 | 1 | 0 | 4.07 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 44 | 0 | 6 | 1 | 1.50 | .213 | 0.79 | 4.7 | 2.4 | 6.8 | 48.0 | 25 | 12 | 8 | 3 | 13 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.19 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 92 | 0 | 2 | 6 | 2.15 | .311 | 1.34 | 8.3 | 3.9 | 8.4 | 62.2 | 57 | 22 | 15 | 7 | 27 | 58 | 0 | 1 | 1 | 0 | 0 | 1 | 5 | 3.95 |