| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 24 | 24 | 10 | 3 | 3.10 | .285 | 1.16 | 6.3 | 4.2 | 7.1 | 168.1 | 118 | 61 | 58 | 9 | 78 | 133 | 1 | 0 | 0 | 1 | 19 | 5 | 4 | 3.60 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 23 | 23 | 12 | 3 | 3.28 | .277 | 1.12 | 7.0 | 3.1 | 5.7 | 164.2 | 127 | 62 | 60 | 13 | 57 | 103 | 4 | 0 | 0 | 2 | 16 | 5 | 3 | 3.91 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 45 | 23 | 23 | 8 | 6 | 5.65 | .346 | 1.57 | 8.6 | 5.5 | 7.2 | 121.0 | 116 | 78 | 76 | 13 | 74 | 97 | 0 | 0 | 0 | 0 | 11 | 2 | 3 | 4.68 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 50 | 20 | 20 | 10 | 4 | 3.98 | .322 | 1.41 | 8.4 | 4.3 | 4.2 | 138.0 | 129 | 65 | 61 | 10 | 66 | 65 | 5 | 0 | 0 | 2 | 11 | 2 | 8 | 4.48 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 63 | 0 | 13 | 1 | 2.23 | .224 | 0.87 | 4.4 | 3.4 | 8.4 | 97.0 | 47 | 25 | 24 | 9 | 37 | 91 | 0 | 11 | 1 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 87 | 38 | 0 | 3 | 1 | 1.32 | .210 | 0.80 | 6.5 | 0.8 | 7.7 | 47.2 | 34 | 8 | 7 | 2 | 4 | 40 | 0 | 10 | 0 | 0 | 0 | 0 | 0 | 2.11 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 23 | 0 | 8 | 2 | 2.91 | .244 | 0.97 | 6.9 | 1.9 | 7.9 | 34.0 | 26 | 13 | 11 | 5 | 7 | 30 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 20 | 0 | 1 | 0 | 2.52 | .265 | 1.08 | 8.6 | 1.1 | 6.1 | 25.0 | 24 | 8 | 7 | 3 | 3 | 17 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 13 | 0 | 0 | 0 | 6.19 | .333 | 1.50 | 8.4 | 5.1 | 11.3 | 16.0 | 15 | 11 | 11 | 3 | 9 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.63 |