| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 33 | 33 | 13 | 14 | 4.51 | .309 | 1.31 | 9.2 | 2.6 | 5.3 | 221.2 | 227 | 119 | 111 | 31 | 63 | 130 | 2 | 0 | 0 | 1 | 17 | 7 | 4 | 4.60 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 32 | 32 | 7 | 19 | 5.12 | .345 | 1.56 | 9.9 | 4.2 | 5.5 | 211.0 | 232 | 134 | 120 | 28 | 98 | 129 | 5 | 0 | 0 | 2 | 14 | 4 | 6 | 4.95 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 32 | 32 | 13 | 14 | 6.15 | .358 | 1.64 | 10.8 | 4.0 | 7.4 | 190.1 | 227 | 134 | 130 | 28 | 85 | 157 | 0 | 0 | 0 | 0 | 13 | 6 | 0 | 4.70 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 94 | 91 | 0 | 8 | 4 | 3.49 | .295 | 1.25 | 8.0 | 3.3 | 10.0 | 131.2 | 117 | 56 | 51 | 10 | 48 | 145 | 0 | 12 | 4 | 0 | 0 | 0 | 2 | 2.88 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 77 | 0 | 7 | 4 | 3.59 | .314 | 1.36 | 7.9 | 4.5 | 7.9 | 97.2 | 85 | 43 | 39 | 11 | 48 | 85 | 0 | 9 | 3 | 0 | 0 | 1 | 2 | 4.24 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 72 | 0 | 6 | 2 | 4.70 | .321 | 1.40 | 7.6 | 5.0 | 7.9 | 82.1 | 69 | 49 | 43 | 15 | 46 | 72 | 0 | 12 | 4 | 0 | 0 | 2 | 4 | 5.38 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 56 | 0 | 4 | 3 | 6.30 | .350 | 1.60 | 10.7 | 3.8 | 5.4 | 60.0 | 71 | 43 | 42 | 9 | 25 | 36 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 5.05 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 7 | 0 | 2 | 0 | 5.82 | .346 | 1.59 | 8.5 | 5.8 | 4.8 | 17.0 | 16 | 12 | 11 | 2 | 11 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.41 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 36 | 1 | 7 | 1 | 5.14 | .374 | 1.77 | 9.4 | 6.5 | 6.9 | 77.0 | 80 | 46 | 44 | 10 | 56 | 59 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 5.42 |