| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 23 | 23 | 9 | 11 | 4.15 | .293 | 1.21 | 7.7 | 3.2 | 8.5 | 165.0 | 141 | 85 | 76 | 22 | 59 | 156 | 5 | 0 | 0 | 1 | 12 | 5 | 2 | 4.01 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 23 | 23 | 7 | 8 | 5.28 | .328 | 1.45 | 10.3 | 2.8 | 4.6 | 119.1 | 136 | 82 | 70 | 17 | 37 | 61 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 4.82 |
| SP | Blue, V.Blue, Vida † # >> | 22 | 1971 | L | 80 | 24 | 24 | 11 | 10 | 3.38 | .287 | 1.18 | 7.6 | 3.1 | 7.5 | 184.0 | 155 | 75 | 69 | 16 | 63 | 153 | 11 | 0 | 0 | 4 | 14 | 4 | 4 | 3.56 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 21 | 21 | 10 | 8 | 5.23 | .325 | 1.42 | 9.9 | 2.9 | 4.4 | 144.2 | 158 | 92 | 84 | 18 | 47 | 70 | 8 | 0 | 0 | 0 | 8 | 4 | 0 | 4.72 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 52 | 0 | 2 | 2 | 1.82 | .271 | 1.10 | 6.0 | 4.0 | 9.4 | 74.1 | 49 | 17 | 15 | 3 | 33 | 77 | 0 | 7 | 2 | 0 | 0 | 1 | 3 | 2.82 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 44 | 0 | 5 | 1 | 3.42 | .317 | 1.34 | 7.5 | 4.6 | 5.9 | 55.1 | 46 | 22 | 21 | 6 | 28 | 36 | 0 | 3 | 3 | 0 | 0 | 3 | 0 | 4.80 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 38 | 0 | 1 | 1 | 3.80 | .338 | 1.51 | 9.8 | 3.8 | 6.8 | 45.0 | 49 | 19 | 19 | 6 | 19 | 34 | 0 | 4 | 0 | 0 | 0 | 1 | 4 | 4.56 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 34 | 0 | 5 | 2 | 2.77 | .272 | 1.12 | 5.8 | 4.4 | 6.5 | 61.2 | 39 | 19 | 19 | 8 | 30 | 44 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.74 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 18 | 0 | 0 | 0 | 8.20 | .404 | 2.04 | 14.5 | 4.5 | 11.0 | 18.2 | 29 | 17 | 17 | 4 | 9 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.94 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 1 | 1 | 0 | 1 | 4.91 | .290 | 1.23 | 9.0 | 2.6 | 2.6 | 7.1 | 7 | 4 | 4 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.14 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 13 | 0 | 2 | 0 | 5.09 | .321 | 1.42 | 10.1 | 3.2 | 5.8 | 17.2 | 19 | 11 | 10 | 0 | 6 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.76 |