| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 33 | 33 | 14 | 16 | 4.22 | .288 | 1.20 | 8.4 | 2.5 | 8.5 | 256.0 | 238 | 128 | 120 | 30 | 70 | 241 | 14 | 0 | 0 | 2 | 18 | 2 | 12 | 3.48 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 32 | 32 | 15 | 7 | 4.05 | .283 | 1.17 | 7.2 | 3.4 | 5.0 | 222.1 | 177 | 103 | 100 | 17 | 83 | 123 | 3 | 0 | 0 | 0 | 21 | 3 | 2 | 4.05 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 31 | 31 | 13 | 15 | 4.72 | .323 | 1.41 | 9.5 | 3.2 | 4.7 | 228.2 | 241 | 135 | 120 | 24 | 81 | 118 | 8 | 0 | 0 | 1 | 16 | 5 | 1 | 4.46 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 30 | 30 | 17 | 11 | 4.42 | .306 | 1.31 | 8.9 | 2.9 | 5.9 | 234.0 | 232 | 121 | 115 | 30 | 75 | 153 | 16 | 0 | 0 | 3 | 14 | 2 | 3 | 4.35 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 72 | 0 | 5 | 6 | 4.48 | .278 | 1.12 | 7.5 | 2.7 | 8.9 | 88.1 | 73 | 46 | 44 | 12 | 26 | 87 | 0 | 12 | 4 | 0 | 0 | 3 | 3 | 3.78 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 41 | 0 | 4 | 2 | 2.14 | .296 | 1.24 | 6.0 | 5.1 | 9.0 | 42.0 | 28 | 10 | 10 | 2 | 24 | 42 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 3.40 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 11 | 0 | 2 | 2 | 2.79 | .293 | 1.24 | 7.0 | 5.0 | 12.0 | 9.2 | 7 | 3 | 3 | 0 | 5 | 12 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 4 | 0 | 1 | 0 | 2.70 | .231 | 0.90 | 6.0 | 3.0 | 12.0 | 3.1 | 2 | 1 | 1 | 1 | 1 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.67 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 3 | 0 | 1 | 0 | 0.00 | .100 | 0.33 | 3.0 | 0.0 | 6.0 | 3.0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1.67 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 14 | 0 | 0 | 0 | 5.56 | .313 | 1.37 | 9.8 | 2.9 | 4.1 | 22.2 | 24 | 14 | 14 | 3 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.82 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 12 | 0 | 1 | 2 | 4.85 | .327 | 1.46 | 9.7 | 3.6 | 4.4 | 55.2 | 59 | 30 | 30 | 8 | 22 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.11 |