| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 35 | 35 | 17 | 11 | 2.80 | .267 | 1.07 | 7.2 | 2.5 | 8.9 | 234.2 | 187 | 77 | 73 | 19 | 65 | 231 | 0 | 0 | 0 | 0 | 27 | 5 | 0 | 2.98 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 33 | 33 | 12 | 19 | 5.33 | .338 | 1.50 | 10.0 | 3.6 | 6.1 | 245.0 | 271 | 155 | 145 | 35 | 97 | 165 | 10 | 0 | 0 | 2 | 12 | 7 | 2 | 4.78 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 33 | 33 | 9 | 11 | 4.96 | .328 | 1.45 | 8.5 | 4.6 | 7.3 | 203.1 | 191 | 125 | 112 | 24 | 103 | 164 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 4.50 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 31 | 31 | 12 | 15 | 5.02 | .343 | 1.54 | 9.7 | 4.1 | 5.9 | 229.1 | 248 | 144 | 128 | 33 | 105 | 151 | 8 | 0 | 0 | 1 | 12 | 6 | 6 | 5.01 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 18 | 0 | 1 | 1 | 0.90 | .189 | 0.70 | 3.2 | 3.2 | 7.7 | 20.0 | 7 | 2 | 2 | 0 | 7 | 17 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 2.35 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 10 | 0 | 2 | 0 | 1.42 | .174 | 0.63 | 6.0 | 0.0 | 9.8 | 12.2 | 8 | 2 | 2 | 2 | 0 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 18 | 0 | 0 | 0 | 1.16 | .263 | 1.07 | 4.3 | 5.5 | 9.0 | 23.1 | 11 | 3 | 3 | 2 | 14 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.96 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 12 | 0 | 0 | 1 | 2.88 | .296 | 1.24 | 7.7 | 3.5 | 4.2 | 56.1 | 48 | 20 | 18 | 3 | 22 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.00 |