| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 34 | 34 | 12 | 15 | 4.60 | .300 | 1.26 | 8.6 | 2.8 | 8.2 | 230.2 | 220 | 123 | 118 | 24 | 71 | 210 | 5 | 0 | 0 | 1 | 19 | 6 | 3 | 3.53 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 33 | 33 | 8 | 15 | 4.85 | .325 | 1.40 | 8.9 | 3.7 | 8.1 | 222.2 | 220 | 125 | 120 | 29 | 92 | 200 | 3 | 0 | 0 | 1 | 13 | 9 | 4 | 4.26 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 32 | 32 | 7 | 17 | 5.68 | .338 | 1.50 | 10.4 | 3.2 | 8.3 | 191.2 | 221 | 132 | 121 | 25 | 67 | 177 | 0 | 0 | 0 | 0 | 12 | 6 | 14 | 3.99 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 32 | 32 | 6 | 21 | 6.64 | .361 | 1.65 | 11.8 | 3.0 | 5.1 | 198.0 | 259 | 161 | 146 | 31 | 67 | 112 | 9 | 0 | 0 | 0 | 12 | 9 | 13 | 5.06 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 31 | 31 | 7 | 15 | 5.84 | .340 | 1.54 | 10.7 | 3.2 | 4.6 | 180.1 | 213 | 131 | 117 | 16 | 64 | 92 | 0 | 0 | 0 | 0 | 16 | 2 | 3 | 4.23 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 80 | 0 | 6 | 3 | 4.37 | .286 | 1.18 | 8.3 | 2.4 | 7.9 | 111.1 | 102 | 62 | 54 | 19 | 29 | 98 | 0 | 4 | 8 | 0 | 0 | 3 | 1 | 4.32 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 82 | 0 | 10 | 0 | 4.03 | .273 | 1.11 | 8.4 | 1.6 | 7.9 | 109.1 | 102 | 49 | 49 | 17 | 19 | 96 | 0 | 5 | 4 | 0 | 0 | 2 | 2 | 3.84 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 67 | 0 | 6 | 4 | 4.04 | .305 | 1.29 | 8.4 | 3.2 | 5.5 | 100.1 | 93 | 46 | 45 | 13 | 36 | 61 | 0 | 7 | 4 | 0 | 0 | 3 | 3 | 4.64 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 21 | 0 | 1 | 2 | 3.99 | .358 | 1.67 | 8.3 | 6.9 | 9.9 | 38.1 | 35 | 17 | 17 | 3 | 29 | 42 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.11 |