| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 36 | 36 | 11 | 12 | 4.07 | .282 | 1.14 | 7.8 | 2.5 | 8.4 | 236.1 | 204 | 117 | 107 | 39 | 66 | 220 | 3 | 0 | 0 | 0 | 20 | 8 | 3 | 4.22 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 34 | 34 | 11 | 12 | 4.89 | .320 | 1.39 | 9.8 | 2.8 | 8.4 | 204.1 | 221 | 117 | 111 | 26 | 63 | 190 | 0 | 0 | 0 | 0 | 17 | 4 | 6 | 3.78 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 85 | 33 | 33 | 7 | 10 | 4.08 | .308 | 1.33 | 8.5 | 3.5 | 4.7 | 172.0 | 163 | 85 | 78 | 23 | 66 | 90 | 0 | 0 | 0 | 0 | 12 | 1 | 2 | 4.86 |
| SP | Reulbach, E.Reulbach, Ed $$ >> | 24 | 1906 | R | 60 | 33 | 33 | 14 | 6 | 3.76 | .300 | 1.28 | 7.0 | 4.6 | 4.0 | 208.1 | 161 | 88 | 87 | 18 | 106 | 93 | 1 | 0 | 0 | 0 | 20 | 1 | 3 | 4.77 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 12 | 10 | 5.14 | .339 | 1.51 | 9.9 | 3.8 | 5.7 | 180.1 | 197 | 118 | 103 | 24 | 76 | 114 | 4 | 0 | 0 | 1 | 13 | 4 | 8 | 4.80 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 80 | 0 | 5 | 11 | 3.81 | .315 | 1.38 | 8.0 | 4.5 | 10.9 | 82.2 | 73 | 41 | 35 | 7 | 41 | 99 | 0 | 43 | 6 | 0 | 0 | 0 | 4 | 3.20 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 82 | 0 | 11 | 2 | 3.82 | .274 | 1.12 | 7.5 | 2.7 | 8.4 | 94.1 | 78 | 40 | 40 | 14 | 28 | 88 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 3.99 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 38 | 0 | 2 | 5 | 5.35 | .331 | 1.43 | 9.0 | 4.1 | 8.5 | 33.2 | 33 | 23 | 20 | 4 | 15 | 31 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.24 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 30 | 0 | 2 | 1 | 2.30 | .282 | 1.12 | 6.7 | 3.5 | 10.5 | 31.1 | 23 | 8 | 8 | 1 | 12 | 36 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 2.45 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 30 | 0 | 1 | 1 | 3.96 | .314 | 1.35 | 10.3 | 2.0 | 10.3 | 36.1 | 41 | 18 | 16 | 6 | 8 | 41 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 3.64 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 26 | 0 | 6 | 1 | 4.84 | .353 | 1.62 | 9.4 | 5.3 | 4.1 | 111.2 | 116 | 63 | 60 | 10 | 65 | 51 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.06 |