| SP | Scherzer, M.Scherzer, Max † $ >> | 33 | 2017 | R | 95 | 36 | 36 | 20 | 8 | 2.65 | .273 | 1.10 | 6.5 | 3.4 | 7.8 | 257.2 | 187 | 78 | 76 | 16 | 97 | 224 | 4 | 0 | 0 | 1 | 30 | 7 | 3 | 3.28 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 33 | 33 | 16 | 12 | 3.35 | .282 | 1.17 | 7.2 | 3.3 | 4.7 | 260.2 | 209 | 107 | 97 | 23 | 95 | 137 | 14 | 0 | 0 | 1 | 21 | 3 | 3 | 4.23 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 85 | 0 | 7 | 4 | 2.25 | .248 | 0.98 | 5.0 | 3.8 | 10.2 | 100.0 | 56 | 25 | 25 | 8 | 42 | 113 | 0 | 15 | 2 | 0 | 0 | 1 | 7 | 3.07 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 32 | 0 | 1 | 3 | 2.63 | .280 | 1.14 | 7.5 | 2.9 | 6.6 | 37.2 | 31 | 11 | 11 | 6 | 12 | 27 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.70 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 22 | 0 | 3 | 1 | 3.18 | .198 | 0.74 | 3.9 | 2.9 | 10.6 | 28.1 | 12 | 10 | 10 | 3 | 9 | 33 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 19 | 0 | 2 | 2 | 2.39 | .255 | 1.03 | 5.5 | 3.8 | 11.1 | 26.1 | 16 | 7 | 7 | 3 | 11 | 32 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.31 |