| SP | Tiant, L.Tiant, Luis $ >> | 28 | 1968 | R | 97 | 34 | 34 | 12 | 17 | 4.68 | .312 | 1.32 | 7.7 | 4.2 | 7.1 | 219.1 | 188 | 120 | 114 | 26 | 102 | 173 | 6 | 0 | 0 | 2 | 16 | 9 | 6 | 4.48 |
| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 33 | 33 | 12 | 11 | 3.39 | .289 | 1.20 | 8.2 | 2.6 | 6.2 | 223.0 | 203 | 90 | 84 | 27 | 65 | 154 | 2 | 0 | 0 | 1 | 22 | 4 | 7 | 4.12 |
| SP | Alexander, P.Alexander, Pete $ >> | 28 | 1915 | R | 88 | 32 | 32 | 14 | 13 | 4.37 | .303 | 1.28 | 9.1 | 2.4 | 5.1 | 226.2 | 229 | 117 | 110 | 32 | 60 | 128 | 6 | 0 | 0 | 1 | 15 | 6 | 4 | 4.58 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 31 | 31 | 11 | 12 | 5.04 | .322 | 1.39 | 9.7 | 2.8 | 7.9 | 194.2 | 210 | 115 | 109 | 39 | 61 | 171 | 2 | 0 | 0 | 0 | 15 | 6 | 3 | 4.89 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 63 | 0 | 5 | 7 | 2.17 | .279 | 1.16 | 6.8 | 3.7 | 9.4 | 66.1 | 50 | 19 | 16 | 4 | 27 | 69 | 0 | 40 | 2 | 0 | 0 | 0 | 1 | 2.92 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 72 | 0 | 4 | 3 | 5.01 | .301 | 1.27 | 7.8 | 3.7 | 9.8 | 82.2 | 71 | 47 | 46 | 11 | 34 | 89 | 0 | 1 | 4 | 0 | 0 | 2 | 4 | 3.89 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 49 | 0 | 2 | 2 | 3.38 | .290 | 1.22 | 7.2 | 4.0 | 9.2 | 50.2 | 40 | 19 | 19 | 4 | 22 | 51 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.32 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 38 | 0 | 3 | 0 | 3.80 | .232 | 0.91 | 6.3 | 1.9 | 7.5 | 47.1 | 33 | 21 | 20 | 7 | 10 | 39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.91 |