| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 25 | 25 | 10 | 9 | 3.70 | .280 | 1.14 | 8.0 | 2.3 | 8.0 | 172.2 | 152 | 71 | 71 | 21 | 44 | 152 | 5 | 0 | 0 | 3 | 14 | 5 | 2 | 3.67 |
| SP | Mathewson, C.Mathewson, Christy $ >> | 28 | 1908 | R | 83 | 24 | 24 | 8 | 9 | 2.98 | .268 | 1.08 | 7.7 | 2.0 | 5.4 | 181.1 | 155 | 67 | 60 | 18 | 41 | 108 | 3 | 0 | 0 | 2 | 16 | 3 | 2 | 3.83 |
| SP | Snell, B.Snell, Blake $$ >> | 25 | 2018 | L | 81 | 23 | 23 | 8 | 10 | 4.11 | .295 | 1.24 | 7.3 | 3.9 | 7.5 | 140.0 | 113 | 67 | 64 | 23 | 61 | 116 | 0 | 0 | 0 | 0 | 10 | 2 | 4 | 4.83 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 71 | 0 | 2 | 2 | 2.55 | .254 | 1.00 | 5.9 | 3.2 | 7.2 | 70.2 | 46 | 20 | 20 | 4 | 25 | 56 | 0 | 8 | 1 | 0 | 0 | 1 | 0 | 3.26 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 37 | 0 | 4 | 3 | 2.41 | .281 | 1.12 | 6.8 | 3.3 | 7.7 | 41.0 | 31 | 11 | 11 | 2 | 15 | 35 | 0 | 4 | 3 | 0 | 0 | 2 | 2 | 3.17 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 29 | 0 | 4 | 2 | 3.00 | .258 | 1.00 | 7.5 | 1.5 | 10.5 | 24.0 | 20 | 9 | 8 | 1 | 4 | 28 | 0 | 6 | 1 | 0 | 0 | 1 | 7 | 1.83 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 21 | 0 | 0 | 2 | 3.91 | .289 | 1.17 | 7.8 | 2.7 | 8.2 | 23.0 | 20 | 10 | 10 | 2 | 7 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.35 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 12 | 0 | 2 | 3 | 6.45 | .302 | 1.30 | 9.2 | 2.7 | 7.6 | 44.2 | 45 | 32 | 32 | 6 | 13 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.98 |