| SP | Vazquez, J.Vazquez, Javier † >> | 33 | 2009 | R | 99 | 27 | 27 | 11 | 12 | 3.49 | .298 | 1.25 | 8.6 | 2.7 | 9.3 | 180.1 | 172 | 80 | 70 | 19 | 54 | 186 | 3 | 0 | 0 | 1 | 16 | 4 | 7 | 3.27 |
| SP | Hanson, T.Hanson, Tommy >> | 22 | 2009 | R | 92 | 27 | 27 | 7 | 12 | 3.88 | .287 | 1.19 | 7.3 | 3.4 | 6.1 | 178.2 | 145 | 78 | 77 | 27 | 67 | 121 | 3 | 0 | 0 | 0 | 15 | 4 | 1 | 4.81 |
| SP | Verlander, J.Verlander, Justin † # >> | 26 | 2009 | R | 88 | 26 | 26 | 15 | 8 | 3.45 | .272 | 1.09 | 7.9 | 2.0 | 9.0 | 190.1 | 166 | 76 | 73 | 23 | 42 | 191 | 8 | 0 | 0 | 2 | 18 | 5 | 3 | 3.31 |
| SP | Beckett, J.Beckett, Josh # >> | 29 | 2009 | R | 81 | 26 | 26 | 10 | 12 | 5.42 | .340 | 1.51 | 10.2 | 3.4 | 7.2 | 162.2 | 184 | 102 | 98 | 31 | 61 | 130 | 2 | 0 | 0 | 0 | 10 | 6 | 3 | 5.12 |
| SP | Dempster, R.Dempster, Ryan >> | 32 | 2009 | R | 57 | 26 | 26 | 8 | 16 | 4.96 | .344 | 1.56 | 10.6 | 3.4 | 7.2 | 163.1 | 192 | 95 | 90 | 31 | 62 | 130 | 1 | 0 | 0 | 0 | 10 | 3 | 6 | 5.07 |
| RP | Soriano, R.Soriano, Rafael >> | 30 | 2009 | R | 93 | 72 | 0 | 3 | 5 | 3.89 | .323 | 1.43 | 8.5 | 4.4 | 9.7 | 88.0 | 83 | 41 | 38 | 10 | 43 | 95 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Clippard, T.Clippard, Tyler >> | 24 | 2009 | R | 85 | 57 | 0 | 4 | 5 | 3.23 | .327 | 1.46 | 7.2 | 6.0 | 10.3 | 75.1 | 60 | 29 | 27 | 6 | 50 | 86 | 0 | 11 | 3 | 0 | 0 | 0 | 5 | 3.75 |
| RP | Aceves, A.Aceves, Alfredo >> | 27 | 2009 | R | 76 | 35 | 0 | 3 | 1 | 3.10 | .275 | 1.11 | 7.9 | 2.2 | 7.0 | 49.1 | 43 | 20 | 17 | 7 | 12 | 38 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Bulger, J.Bulger, Jason >> | 31 | 2009 | R | 70 | 16 | 0 | 0 | 0 | 4.32 | .315 | 1.38 | 9.0 | 3.9 | 10.7 | 16.2 | 16 | 8 | 8 | 2 | 7 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| SP | Bergesen, B.Bergesen, Brad >> | 23 | 2009 | R | 40 | 3 | 0 | 0 | 0 | 7.36 | .353 | 1.64 | 15.0 | 3.0 | 12.0 | 3.2 | 5 | 3 | 3 | 1 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.67 |