| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 88 | 25 | 25 | 14 | 5 | 2.69 | .260 | 1.02 | 5.7 | 3.5 | 9.3 | 160.2 | 101 | 50 | 48 | 14 | 63 | 166 | 0 | 0 | 0 | 0 | 20 | 5 | 5 | 3.34 |
| SP | Fernandez, J.Fernandez, Jose † >> | 21 | 2013 | R | 82 | 25 | 25 | 19 | 1 | 2.39 | .250 | 0.98 | 5.8 | 3.1 | 7.6 | 169.2 | 108 | 48 | 45 | 12 | 59 | 143 | 0 | 0 | 0 | 0 | 21 | 3 | 1 | 3.33 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 24 | 22 | 12 | 3 | 2.57 | .262 | 1.03 | 6.6 | 2.6 | 6.4 | 126.0 | 93 | 42 | 36 | 11 | 37 | 90 | 0 | 0 | 0 | 0 | 11 | 4 | 3 | 3.68 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 83 | 25 | 24 | 9 | 5 | 3.86 | .308 | 1.30 | 7.7 | 4.0 | 8.4 | 128.1 | 110 | 58 | 55 | 25 | 57 | 120 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 5.09 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 86 | 45 | 0 | 3 | 1 | 1.83 | .210 | 0.80 | 4.1 | 3.1 | 11.3 | 59.0 | 27 | 13 | 12 | 6 | 20 | 74 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 2.83 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 40 | 0 | 2 | 2 | 2.96 | .267 | 1.05 | 5.2 | 4.4 | 8.4 | 45.2 | 26 | 15 | 15 | 5 | 22 | 42 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 4.18 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 54 | 0 | 1 | 1 | 1.86 | .227 | 0.88 | 5.4 | 2.5 | 11.2 | 53.1 | 32 | 13 | 11 | 3 | 15 | 66 | 0 | 39 | 3 | 0 | 0 | 0 | 4 | 2.09 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 45 | 0 | 2 | 3 | 3.33 | .311 | 1.32 | 5.3 | 6.8 | 9.4 | 48.2 | 28 | 19 | 18 | 5 | 36 | 50 | 0 | 3 | 3 | 0 | 0 | 2 | 8 | 4.65 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 24 | 0 | 2 | 1 | 5.76 | .306 | 1.28 | 6.5 | 5.0 | 10.1 | 25.0 | 18 | 16 | 16 | 9 | 14 | 28 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 7.24 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 4 | 0 | 1 | 1 | 2.16 | .275 | 1.14 | 5.6 | 5.1 | 6.8 | 16.2 | 10 | 4 | 4 | 1 | 9 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |