| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 95 | 36 | 36 | 18 | 6 | 3.62 | .281 | 1.12 | 7.6 | 2.5 | 8.4 | 226.1 | 192 | 92 | 91 | 21 | 62 | 211 | 6 | 0 | 0 | 1 | 22 | 11 | 6 | 3.31 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 84 | 34 | 34 | 16 | 8 | 4.18 | .274 | 1.10 | 7.7 | 2.2 | 6.4 | 217.2 | 186 | 106 | 101 | 31 | 54 | 154 | 6 | 0 | 0 | 2 | 15 | 6 | 1 | 4.27 |
| SP | Fernandez, J.Fernandez, Jose $$ >> | 21 | 2013 | R | 83 | 31 | 31 | 13 | 10 | 4.01 | .304 | 1.27 | 7.8 | 3.6 | 8.3 | 193.0 | 168 | 93 | 86 | 21 | 77 | 177 | 0 | 0 | 0 | 0 | 19 | 8 | 1 | 3.90 |
| RP | Williams, D.Williams, Devin # >> | 28 | 2023 | R | 70 | 33 | 0 | 4 | 3 | 4.54 | .409 | 2.08 | 9.0 | 10.1 | 9.5 | 33.2 | 33 | 17 | 17 | 3 | 37 | 35 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.42 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 48 | 0 | 3 | 1 | 3.24 | .286 | 1.14 | 6.7 | 3.6 | 9.2 | 50.0 | 37 | 18 | 18 | 5 | 20 | 51 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 3.64 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 63 | 0 | 3 | 3 | 2.89 | .287 | 1.18 | 7.6 | 3.0 | 8.9 | 65.1 | 55 | 21 | 21 | 7 | 22 | 64 | 0 | 41 | 3 | 0 | 0 | 2 | 2 | 3.54 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 59 | 0 | 6 | 5 | 3.23 | .289 | 1.21 | 7.4 | 3.5 | 11.1 | 69.2 | 57 | 26 | 25 | 11 | 27 | 85 | 0 | 5 | 8 | 0 | 0 | 1 | 4 | 3.83 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 6 | 0 | 0 | 0 | 0.00 | .471 | 2.67 | 15.0 | 9.0 | 9.0 | 3.0 | 5 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 77 | 31 | 30 | 6 | 12 | 5.05 | .333 | 1.46 | 9.9 | 3.3 | 8.7 | 173.0 | 190 | 98 | 97 | 24 | 63 | 167 | 0 | 0 | 0 | 0 | 14 | 6 | 2 | 4.07 |