| SP | Martinez, P.Martinez, Pedro † $ >> | 29 | 2000 | R | 100 | 26 | 26 | 9 | 9 | 4.11 | .286 | 1.18 | 7.8 | 2.8 | 9.0 | 199.1 | 173 | 93 | 91 | 20 | 63 | 200 | 8 | 0 | 0 | 5 | 12 | 4 | 6 | 3.31 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 24 | 24 | 6 | 9 | 4.42 | .300 | 1.25 | 8.5 | 2.8 | 8.5 | 154.2 | 146 | 78 | 76 | 24 | 48 | 146 | 0 | 0 | 0 | 0 | 15 | 5 | 6 | 4.16 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 25 | 23 | 10 | 5 | 4.19 | .320 | 1.40 | 8.7 | 3.9 | 9.3 | 154.2 | 149 | 83 | 72 | 19 | 67 | 159 | 0 | 1 | 0 | 0 | 15 | 2 | 3 | 3.88 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 76 | 0 | 8 | 1 | 4.01 | .300 | 1.24 | 8.4 | 2.8 | 10.9 | 74.0 | 69 | 34 | 33 | 12 | 23 | 90 | 0 | 5 | 4 | 0 | 0 | 3 | 1 | 3.73 |
| RP | Soriano, R.Soriano, Rafael # >> | 24 | 2003 | R | 82 | 68 | 0 | 6 | 4 | 4.60 | .303 | 1.28 | 9.0 | 2.6 | 9.0 | 74.1 | 74 | 39 | 38 | 12 | 21 | 74 | 0 | 7 | 6 | 0 | 0 | 2 | 0 | 4.04 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 76 | 39 | 0 | 2 | 4 | 3.38 | .291 | 1.23 | 7.9 | 3.2 | 9.6 | 48.0 | 42 | 18 | 18 | 7 | 17 | 51 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 3.83 |
| RP | Holland, G.Holland, Greg # >> | 27 | 2013 | R | 68 | 37 | 0 | 1 | 4 | 4.13 | .305 | 1.29 | 9.3 | 2.5 | 9.8 | 32.2 | 33 | 19 | 15 | 6 | 9 | 35 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 4.19 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 14 | 2 | 2 | 3 | 5.11 | .345 | 1.54 | 10.9 | 3.4 | 6.8 | 24.2 | 29 | 14 | 14 | 6 | 9 | 18 | 0 | 3 | 0 | 0 | 1 | 1 | 1 | 6.00 |