| SP | Gallen, Z.Gallen, Zac $$ >> | 26 | 2022 | R | 93 | 34 | 34 | 18 | 9 | 3.80 | .298 | 1.24 | 7.9 | 3.3 | 8.1 | 210.2 | 184 | 93 | 89 | 25 | 77 | 188 | 3 | 0 | 0 | 2 | 16 | 7 | 5 | 3.96 |
| SP | Clemens, R.Clemens, Roger † # >> | 24 | 1986 | R | 79 | 35 | 35 | 16 | 13 | 4.19 | .306 | 1.29 | 8.5 | 3.1 | 6.6 | 243.0 | 229 | 113 | 113 | 36 | 85 | 178 | 10 | 0 | 0 | 4 | 17 | 8 | 6 | 4.61 |
| SP | Fernandez, S.Fernandez, Sid $$ >> | 23 | 1985 | L | 53 | 34 | 34 | 18 | 5 | 3.13 | .286 | 1.18 | 6.8 | 3.8 | 8.1 | 227.0 | 171 | 87 | 79 | 31 | 96 | 205 | 0 | 0 | 0 | 0 | 25 | 6 | 2 | 4.32 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 96 | 36 | 36 | 15 | 17 | 4.65 | .303 | 1.27 | 8.5 | 3.0 | 10.3 | 224.1 | 212 | 118 | 116 | 35 | 74 | 256 | 1 | 0 | 0 | 1 | 20 | 6 | 4 | 3.82 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 17 | 0 | 2 | 2 | 6.58 | .373 | 1.75 | 13.0 | 2.9 | 8.3 | 65.2 | 94 | 49 | 48 | 10 | 21 | 60 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 4.22 |
| CL | Street, H.Street, Huston † $$ >> | 29 | 2012 | R | 95 | 65 | 0 | 6 | 4 | 2.10 | .272 | 1.12 | 6.1 | 4.1 | 9.9 | 68.2 | 46 | 18 | 16 | 4 | 31 | 75 | 0 | 42 | 4 | 0 | 0 | 0 | 0 | 2.93 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 90 | 53 | 0 | 4 | 1 | 2.17 | .221 | 0.82 | 4.8 | 2.6 | 9.6 | 62.1 | 33 | 15 | 15 | 5 | 18 | 66 | 0 | 8 | 5 | 0 | 0 | 2 | 0 | 2.89 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 57 | 0 | 3 | 2 | 3.45 | .295 | 1.17 | 9.3 | 1.3 | 9.9 | 57.1 | 59 | 22 | 22 | 9 | 8 | 63 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 3.53 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 76 | 0 | 2 | 2 | 4.21 | .315 | 1.37 | 9.1 | 3.3 | 8.1 | 83.1 | 84 | 42 | 39 | 11 | 30 | 75 | 0 | 1 | 4 | 0 | 0 | 1 | 9 | 4.04 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 30 | 0 | 2 | 1 | 1.56 | .262 | 1.04 | 6.9 | 2.6 | 7.9 | 34.2 | 26 | 6 | 6 | 1 | 10 | 30 | 0 | 0 | 1 | 0 | 0 | 1 | 5 | 2.59 |
| RP | Brewer, J.Brewer, Jim # >> | 35 | 1972 | L | 70 | 29 | 0 | 2 | 1 | 3.86 | .280 | 1.07 | 6.4 | 3.2 | 6.6 | 42.0 | 30 | 19 | 18 | 11 | 15 | 31 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 6.29 |
| SP | Carlton, S.Carlton, Steve # >> | 28 | 1972 | L | 70 | 31 | 31 | 15 | 10 | 3.89 | .315 | 1.33 | 8.7 | 3.4 | 7.1 | 217.1 | 209 | 96 | 94 | 29 | 81 | 172 | 5 | 0 | 0 | 2 | 18 | 10 | 5 | 4.41 |