| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 22 | 22 | 6 | 6 | 3.68 | .267 | 1.07 | 7.0 | 2.7 | 10.9 | 144.1 | 112 | 65 | 59 | 17 | 43 | 175 | 0 | 0 | 0 | 0 | 15 | 3 | 0 | 3.06 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 21 | 21 | 8 | 7 | 5.35 | .340 | 1.51 | 9.4 | 4.2 | 6.9 | 136.1 | 142 | 86 | 81 | 20 | 64 | 104 | 3 | 0 | 0 | 1 | 8 | 5 | 1 | 4.90 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 73 | 21 | 20 | 8 | 10 | 5.52 | .331 | 1.44 | 9.9 | 3.1 | 6.8 | 135.1 | 148 | 89 | 83 | 27 | 47 | 102 | 5 | 0 | 1 | 0 | 6 | 6 | 4 | 5.27 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 56 | 0 | 7 | 1 | 2.68 | .265 | 1.05 | 6.7 | 2.8 | 8.8 | 74.0 | 55 | 23 | 22 | 7 | 23 | 72 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.30 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 43 | 0 | 6 | 3 | 3.00 | .260 | 1.04 | 8.3 | 1.0 | 8.0 | 54.0 | 50 | 18 | 18 | 7 | 6 | 48 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 3.30 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 29 | 0 | 3 | 1 | 2.27 | .277 | 1.12 | 7.5 | 2.8 | 11.1 | 35.2 | 29 | 9 | 9 | 5 | 11 | 43 | 0 | 7 | 0 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 16 | 0 | 4 | 0 | 2.76 | .319 | 1.35 | 5.1 | 7.3 | 11.8 | 16.1 | 9 | 5 | 5 | 2 | 13 | 21 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.63 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 77 | 22 | 0 | 1 | 2 | 7.20 | .362 | 1.70 | 10.8 | 4.5 | 10.8 | 20.0 | 24 | 16 | 16 | 4 | 10 | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.70 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 73 | 20 | 0 | 1 | 0 | 4.01 | .302 | 1.30 | 8.3 | 3.8 | 9.0 | 24.2 | 22 | 11 | 11 | 4 | 10 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.42 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 12 | 1 | 3 | 1 | 5.02 | .330 | 1.46 | 9.9 | 3.2 | 6.9 | 61.0 | 67 | 34 | 34 | 11 | 22 | 47 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.93 |