| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 26 | 26 | 11 | 4 | 4.66 | .304 | 1.29 | 9.1 | 2.5 | 10.5 | 156.1 | 158 | 83 | 81 | 26 | 44 | 182 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.74 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 25 | 25 | 10 | 10 | 4.68 | .314 | 1.33 | 9.2 | 2.9 | 8.9 | 163.1 | 166 | 94 | 85 | 24 | 52 | 161 | 1 | 0 | 0 | 0 | 12 | 6 | 9 | 4.01 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 89 | 25 | 25 | 10 | 10 | 4.09 | .318 | 1.35 | 9.5 | 2.7 | 9.3 | 165.0 | 174 | 77 | 75 | 22 | 49 | 171 | 2 | 0 | 0 | 1 | 15 | 8 | 1 | 3.70 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 81 | 25 | 25 | 9 | 11 | 5.28 | .304 | 1.30 | 9.3 | 2.4 | 8.6 | 162.0 | 167 | 95 | 95 | 32 | 44 | 155 | 7 | 0 | 0 | 2 | 10 | 1 | 2 | 4.49 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 23 | 23 | 7 | 11 | 5.19 | .319 | 1.39 | 9.3 | 3.2 | 6.7 | 149.0 | 154 | 92 | 86 | 37 | 53 | 111 | 8 | 0 | 0 | 2 | 11 | 2 | 2 | 5.85 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 66 | 0 | 4 | 3 | 2.35 | .268 | 1.06 | 6.7 | 2.8 | 9.2 | 95.2 | 71 | 29 | 25 | 8 | 30 | 97 | 0 | 5 | 1 | 0 | 0 | 4 | 0 | 3.13 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 56 | 0 | 2 | 4 | 2.91 | .259 | 1.03 | 5.7 | 3.6 | 9.7 | 65.0 | 41 | 22 | 21 | 12 | 26 | 70 | 0 | 7 | 2 | 0 | 0 | 1 | 6 | 4.49 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 42 | 0 | 4 | 1 | 3.19 | .241 | 0.95 | 7.1 | 1.5 | 10.4 | 53.2 | 42 | 20 | 19 | 7 | 9 | 61 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 83 | 33 | 0 | 3 | 3 | 2.35 | .238 | 0.94 | 7.3 | 1.2 | 9.7 | 38.1 | 31 | 11 | 10 | 3 | 5 | 41 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 2.26 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 27 | 0 | 3 | 2 | 3.30 | .237 | 0.93 | 6.6 | 1.8 | 11.7 | 30.0 | 22 | 11 | 11 | 7 | 6 | 39 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 4.03 |